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Clinical practice LCS program finds more disease than NLST

AuntMinnie

Over a five-year period, a clinical practice lung cancer screening program at Duke University Medical Center in Durham, NC, found more disease than did the National Lung Screening Trial (NLST), researchers have reported. It also found more stage IV disease, wrote a team led by Kyle Lafata, PhD. “As versus 2.4%. Specificity 83.8%

Disease 83
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CT-FFR shows how smoking affects heart volume-to-myocardial mass ratio

AuntMinnie

We found that] current and former smoking were independently associated with lower [V/M] in participants with coronary artery disease," the group noted. Mechanisms driving low V/M in smokers and the potential use of V/M as a surrogate marker of vascular health and predictor of downstream clinical outcomes require further study.

Disease 88
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REBEL Core Cast 107.0 – Vertebral Osteomyelitis

REBEL EM

Take Home Points Clinical presentation is very nonspecific; evaluate all patients presenting with back pain for infectious risk factors. MRI is key to diagnosis, obtain this imaging in all patients who raise clinical suspicion Patients with hemodynamic instability and neurologic compromise warrant empiric antibiotics.

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GE HealthCare Announces FES PET Imaging Recommendation in NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines)

Imaging Technology

Currently, when treating metastatic breast cancer patients, oncologists base clinical decisions on diagnostic tools including biopsy results which only represent the sampled area of the tumor. GE HealthCare’s Cerianna , available in the U.S., is the only FDA approved FES PET imaging agent. In the U.S.,

Clinic 67
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Weekend admission for TIPS procedure tied to higher mortality risk

AuntMinnie

Weekend admission for transjugular intrahepatic portosystemic shunt (TIPS) procedures is tied to higher mortality risk and post-procedure morbidity, suggest findings published June 12 in Clinics and Research in Hepatology and Gastroenterology. Researchers led by Renxi Li from George Washington University in Washington, D.C.,

Hospital 105
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REBEL Core Cast 85.0 – Superficial Venous Thrombosis

REBEL EM

Cosmi 2015 ) Risk factors of complications of SVT (such as propagation of clot into deep veins) include male gender, history of VTE, cancer, SVT in a non-varicose vein, large SVT >5 cm, or SVT involving the sapheno-femoral junction (SFJ). Risk factors for the development of SVT are similar to those of VTE.

Disease 52
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Mount Sinai Study Calls for Major Changes in the Way People With Comorbidities Are Selected by Physicians for Lung Cancer Screening

Imaging Technology

It was prompted by the fact that smokers have an increased risk of not just lung cancer but complex comorbidities—including cardiovascular or cerebrovascular disease and chronic obstructive pulmonary disease—from their tobacco exposure. That, the researchers said, is part of the problem.