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F-18 fluorothymidine (FLT) PET can identify early acute gastrointestinal graft versus host disease (GVHD) after patients undergo bone marrow transplants, according to a study published December 13 in Radiology: Imaging Cancer. Blood cancers start in the cells of the immune system or in blood-forming tissue, such as the bone marrow.
When radiologists interpretations are indeterminate, a commercially available deep learning algorithm could find clinically significant prostate cancer with improved specificity while maintaining sensitivity, suggested research published March 11 in Radiology. A majority (179) of participants underwent multiparametric MRI, the authors noted.
The study highlights how radiomics can help stratify risk in DCIS cases compared with clinical and qualitative imaging information alone, noted lead authors Kalina Slavkova, PhD, of Columbia University in New York City, and Ruya Kang, PhD, of Brown University in Providence, RI. About 20% of new breast cancers in the U.S.
Columbia University researchers in New York City have reported that worsening depression in older adults is related to higher levels of Alzheimers disease pathology, specifically the accumulation of tau protein. The study was published April 9 in the American Journal of Geriatric Psychiatry. The full study can be found here.
Over a five-year period, a clinical practice lung cancer screening program at Duke University Medical Center in Durham, NC, found more disease than did the National Lung Screening Trial (NLST), researchers have reported. It also found more stage IV disease, wrote a team led by Kyle Lafata, PhD. “As versus 2.4%. Specificity 83.8%
The finding is from a preliminary analysis of 23 patients enrolled in an ongoing clinical trial, noted Giorgio Brembilla, MD, PhD, of the IRCCS San Raffaele Scientific Institute in Milan, Italy. The trial will eventually enroll 167 undiagnosed patients with suspected disease who have been referred for biopsies, Brembilla noted.
Patients with less tau pathology on PET scans may respond better to treatment with the new Alzheimer’s disease drug donanemab, according to an October 25 news report in the journal Practical Neurology. Research suggests that the accumulation of these proteins is a continuous process that starts decades before the onset of symptoms.
AI-guided point-of-care ultrasound (POCUS) can accurately detect tuberculosis (TB), according to research presented April 14 at the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) conference in Vienna, Austria. The technology may have applications in clinically underserved areas, Suttels said.
Deuterium metabolic imaging (DMI) was highly aligned with F-18 FDG-PET -- a cornerstone of dementia diagnostics -- in patients with Alzheimer's disease in a study published April 8 in Radiology. They compared the DMI results to clinical FDG-PET data from patient records. A graphical abstract of the study. Image courtesy of RSNA.
CT imaging shows that severe acute respiratory disease events can be caused by quantitative interstitial abnormalities (QIA) -- that is, small irregularities that don't necessarily meet diagnostic criteria for advanced pulmonary diseases but show up on CT exams over time, a study published April 30 in Radiology has reported.
Alzheimer’s disease (AD) research centers saw a 77% drop in participants enrolling in clinical trials due to the COVID-19 pandemic, according to a study conducted by epidemiologists at the University of Pittsburgh. Few recruitment approaches have been directly tested via intervention trials at Alzheimer’s disease centers, they added.
ChatGPT-4 outperformed human clinicians in determining pretest and post-test disease probability after a negative test result involving chest radiographs and mammograms, according to a research letter published December 11 in JAMA Network Open.
Benign breast disease diagnosed through percutaneous biopsy increases the overall risk of developing breast cancer, according to research published December 13 in JAMA Surgery. Benign breast disease makes up about 75% of breast biopsy diagnoses. The study included data from 4,819 women with a median age of 51.
A predictive model combining multiple ultrasonic parameters could discriminate between different liver diseases in a study published March 19 in Radiology. These findings are important for noninvasive assessment of the MAFLD disease process,” the Liu team wrote. The results have been promising when compared to liver biopsy.
The percentage of lung fibrosis quantified on CT pulmonary angiograms (CTPA) by an AI model is associated with increased risk of mortality -- and boosts clinicians' ability to predict the survival of lung disease patients, researchers have found. The results were published February 6 in Radiology. Images courtesy of the RSNA. "[We
Deuterium metabolic imaging (DMI) can reveal impaired brain glucose metabolism in patients with Alzheimer’s disease, according to a study published July 16 in Radiology. tesla have shown promise, yet performing DMI with a 3-tesla MRI system could facilitate its use in clinical settings, as these scanners are more widely available, they noted.
This legislation would create that system, improving diagnoses and encouraging the adoption of AI devices in clinical settings. Over three-fourths of all clinical AI in the U.S. Bill proponents say this inconsistency will negatively impact clinical AI adoption and patient access to these tools. However, the U.S.
They estimated the likely benefit from endocrine therapy after positive and negative F-18 FES PET scans, as well as the risk ratio of clinical benefit compared between the two. Ultimately, ER-positive breast cancer represents a large subset of the disease, and endocrine therapies remain foundational in treatment, the researchers noted.
Food and Drug Administration (FDA) has approved Eli Lilly's drug donanemab (Kisunla) for the treatment of early Alzheimer's disease, including mild cognitive impairment or mild dementia. According to clinical trials, amyloid PET scans showed that donanemab reduced amyloid plaques by up to 84% after 18 months of treatment.
Our scans show where there is patchy ventilation in patients with lung disease, and show us which parts of the lung improve with treatment," Thelwall said in a statement released by the university. The gas can be safely inhaled and exhaled by patients; MRI exams then show where in the lungs the gas has reached, according to the group.
Photon-counting CT may serve as an alternative to MRI for assessing liver fat in patients with fatty liver disease, according to an article published September 24 in Radiology. The disease affects up to 24% of the population in the U.S. and can lead to cirrhosis and even cancer if left untreated. (A) in the MASLD cohort.
A new paper published in Clinical Imaging details the impact of a high-resolution CT reporting template catered specifically to interstitial lung disease.
PET scans have revealed specific brain pathology that may drive sleep disturbances in Alzheimer’s disease patients, according to a study published February 8 in the Journal of the Neurological Sciences. Of these, 119 (43%) had normal cognition, 132 (24%) had mild cognitive impairment, and three (2%) had Alzheimer’s disease.
PET, CT, and MRI use for assessing coronary artery disease increased in Medicare patients from 2018 to 2022, while SPECT and stress echocardiography declined over the same period, researchers have reported. Taken together, these findings call for efforts to address barriers impeding wider uptake of PET,” the group wrote.
Chest dynamic digital radiography (DDR) may have received a boost toward clinical use in patients with lung disorders, with researchers developing AI to perform time-consuming analysis involved in the technology, according to researchers in New York City.
Middlebrooks, MD, Mayo Clinic, Jacksonville, FL Erik H. Middlebrooks, MD, of the Mayo Clinic in Jacksonville, FL. Importantly, we are gaining deeper insights into disease processes themselves, which enhances our ability to diagnose and potentially treat conditions that were previously beyond our reach." Middlebrooks, MD.
Preliminary studies suggest the tracer may also be effective in patients with earlier, more treatable stages of the disease, yet most of these studies have been retrospective and subject to a large risk of bias, the authors noted. The full study is available here.
Ultrahigh-spatial-resolution photon-counting detector CT (PCCT) improves the evaluation of coronary artery disease (CAD) -- enabling the reclassification of disease to a lower category in 54% of patients, researchers have found. Curved multiplanar reconstructions with 0.6-mm mm (yellow outline), 0.4-mm mm (blue outline), and 0.2-mm
Of these, 1,088 (both CT and MRI exams) were used in a training set that included segmentations of 80 anatomic structures commonly used for measuring volume, characterizing disease, surgical planning, and opportunistic screening, while 55 (MRI exams only) were included in an internal test set. Example MRI scans in the training dataset.
"The results are encouraging as they demonstrate the potential of expanding the role of CT imaging from conventional disease diagnosis to opportunistic proactive screening," study senior author Seungho Ryu, MD, PhD, also of Sungkyunkwan University School of Medicine, said in a statement released by the RSNA.
Clinical analytics firm Covera Health has launched an AI-powered platform called Protect Her, which identifies early signs of breast cancer, cardiovascular disease, and osteoporosis during routine scans.
and radiology has learned much since then, according to experts who directly dealt with the diseases impact. Rengan and colleagues developed clinical guidance for the American Society for Radiation Oncology (ASTRO) on best practices while treating cancer patients in this medical domain, as well as workforce considerations.
A PET study has revealed that women over the age of 70 who took menopausal hormone therapy (HT) more than a decade before have faster brain tau accumulation -- a key indicator of Alzheimers disease. The findings may inform [Alzheimers disease] risk discussions relating to womens reproductive health and treatment, the group wrote.
In further research highlighted at the meeting, Jordan Strom, MD, of Beth Israel Deaconess Medical Center in Boston shared study findings that indicate ultrasound-enhancing agents can improve the accuracy and reliability of a standard echocardiogram performed to evaluate heart disease.
Gastrointestinal imagers should use high-quality MR enterography for complex inflammatory bowel disease (IBD) cases that can't be dealt with using intestinal ultrasound, even though both tests contribute to overall assessment, said an expert leading an advanced course on imaging Crohn's disease at ECR 2025. "MR
Is portable MRI suitable for finding abnormalities in the brains of patients receiving new amyloid-targeting therapy for Alzheimer’s disease? Clinical researchers are about to find out.
PET brain scans show persistent brain inflammation in patients with multiple sclerosis (MS), despite being treated with high-efficacy disease-modifying therapies, according to a recent study by researchers in Boston. Image courtesy of Clinical Nuclear Medicine. The full article is available here.
SimonOne utilizes AI, advanced clinical protocols and the “best available” equipment to detect diseases before symptoms arise, the PE-backed group said Thursday.
Shiv Patil, a student and researcher from the University of Pennsylvania, presented an F-18 NaF-PET/CT study that found the approach visualized biologically active vascular microcalcification in patients at early stages of the disease versus healthy volunteers.
ALZ-NET is a voluntary healthcare provider-enrolled network collecting real-world clinical and imaging data from people evaluated for or treated with new Alzheimers disease treatments.
PET scans typically used for diagnosing prostate cancer may have value in detecting inflammatory bowel disease (IBD), according to a case series published December 8 in Clinical and Experimental Gastroenterology. Image courtesy of Clinical and Experimental Gastroenterology. The full study is available here.
SINGAPORE – MR elastography is a leading noninvasive approach for imaging liver fibrosis, yet a new technique known as “3D MRE” promises to open new opportunities for diagnosing chronic liver disease, according to a leading expert in the field. and the world.
Powered by the Oxford, England-based company's cortical disarray measurement technology, CDM Insights allows for clinical assessment of the brain's microstructures via MRI scans. Healthcare practitioners can use this data to evaluate patients with neurodegenerative disorders such as Alzheimer's disease.
The finding is from a study that showed greater brain metabolic decline in patients with the disease than those without over 3.8 years, noted corresponding author Kejal Kantarci, MD, of the Mayo Clinic in Rochester, MN, and colleagues. DLB is the second most common neurodegenerative dementia after Alzheimers disease.
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