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Research Spotlight: Validating an MRI Biomarker for Early Onset Alzheimer’s Disease

Imaging Technology

Is there a signature biomarker for younger/early-onset Alzheimer’s Disease (EOAD)? Sporadic early-onset Alzheimer’s disease (EOAD) is rare and understudied. Sporadic early-onset Alzheimer’s disease (EOAD) is rare and understudied. What Question Were You Investigating? What Were Your Findings?

Disease 111
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Photon-counting CT emerges as alternative for assessing fatty liver disease

AuntMinnie

Photon-counting CT may serve as an alternative to MRI for assessing liver fat in patients with fatty liver disease, according to an article published September 24 in Radiology. The disease affects up to 24% of the population in the U.S. The disease affects up to 24% of the population in the U.S. in the MASLD cohort.

Disease 111
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Diagnosing Pediatric Crohn Disease With Radiomic and Clinical Data

Imaging Technology

milla1cf Wed, 08/02/2023 - 19:58 August 2, 2023 — An accepted manuscript published in the American Journal of Roentgenology (AJR) found that deploying a radiomic-based model with T2-weighted MRI data could increase diagnostic accuracy for pediatric Crohn disease (CD). and accuracy of 89.6%. and accuracy of 89.6%.

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DMI feasible in Alzheimer’s disease patients

AuntMinnie

Deuterium metabolic imaging (DMI) can reveal impaired brain glucose metabolism in patients with Alzheimer’s disease, according to a study published July 16 in Radiology. However, the use of PET remains limited by its higher cost and lower availability than MRI, according to the authors.

Disease 103
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Cardiac PET use increases in coronary artery disease

AuntMinnie

PET, CT, and MRI use for assessing coronary artery disease increased in Medicare patients from 2018 to 2022, while SPECT and stress echocardiography declined over the same period, researchers have reported. Stress MRI (3,932 procedures) was the least commonly used modality. In comparison, SPECT was six times more frequent (1.3

Disease 89
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Extracardiac findings common on CT, MRI

AuntMinnie

Clinically significant extracardiac findings are common on CT and MRI imaging and are especially associated with exam indication and patient age, researchers have reported. Their assessment included information from 208,506 cardiac CT exams and 228,462 cardiac MRI exams entered into the registry between January 2011 and November 2023.

MRI 52
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FDA approves donanemab for Alzheimer's disease

AuntMinnie

Food and Drug Administration (FDA) has approved Eli Lilly's drug donanemab (Kisunla) for the treatment of early Alzheimer's disease, including mild cognitive impairment or mild dementia. According to clinical trials, amyloid PET scans showed that donanemab reduced amyloid plaques by up to 84% after 18 months of treatment.

Disease 98