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New analysis supports use of FES-PET in breast cancer patients

AuntMinnie

F-18 fluoroestradiol (FES)-PET scans can predict whether or not endocrine therapy may be effective in women with estrogen receptor (ER)-positive breast cancer, according to a study published March 13 in the Journal of Nuclear Medicine. Image courtesy of the Journal of Nuclear Medicine. A visual abstract of the analysis.

PET Scan 227
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ECR: PET/MRI highly effective for detecting prostate cancer

AuntMinnie

The finding is from a preliminary analysis of 23 patients enrolled in an ongoing clinical trial, noted Giorgio Brembilla, MD, PhD, of the IRCCS San Raffaele Scientific Institute in Milan, Italy. The trial will eventually enroll 167 undiagnosed patients with suspected disease who have been referred for biopsies, Brembilla noted.

MRI 260
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FES-PET shows promise staging patients with low-grade breast cancer

AuntMinnie

Preliminary studies suggest the tracer may also be effective in patients with earlier, more treatable stages of the disease, yet most of these studies have been retrospective and subject to a large risk of bias, the authors noted. The full study is available here.

PET Scan 283
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Groups aim to standardize nuclear medicine imaging of CV infections

AuntMinnie

The recommendations could improve patient care, as current clinical tools are often insufficient in complicated cases, noted lead author of the guidance Jamieson Bourque, MD, of the University of Virginia Health System in Charlottesville. The recommendations emphasize the complementary nature of these advanced nuclear medicine exams.

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New PET tracer developed for breast cancer

AuntMinnie

The study was published February 13 in the Journal of Nuclear Medicine. Image courtesy of the Journal of Nuclear Medicine. Thus, with further development in larger trials, Ga-68 FZ-NR-1 could play a significant clinical role, they suggested. The full study is available here.

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PET reveals patient responses to new Alzheimer’s disease drug

AuntMinnie

Patients with less tau pathology on PET scans may respond better to treatment with the new Alzheimer’s disease drug donanemab, according to an October 25 news report in the journal Practical Neurology. Research suggests that the accumulation of these proteins is a continuous process that starts decades before the onset of symptoms.

Disease 298
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FAPI-PET/CT outperforms FDG-PET/CT in women with invasive breast cancer

AuntMinnie

PET/CT imaging using gallium-68 (Ga-68) Fibroblast activation protein inhibitor (FAPI) radiotracer over F-18 FDG appears promising in women with invasive lobular carcinoma (ILC), according to a study published March 14 in the Journal of Nuclear Medicine. Image courtesy of the Journal of Nuclear Medicine.