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Groups aim to standardize nuclear medicine imaging of CV infections

AuntMinnie

The recommendations could improve patient care, as current clinical tools are often insufficient in complicated cases, noted lead author of the guidance Jamieson Bourque, MD, of the University of Virginia Health System in Charlottesville. The recommendations emphasize the complementary nature of these advanced nuclear medicine exams.

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PET reveals patient responses to new Alzheimer’s disease drug

AuntMinnie

Patients with less tau pathology on PET scans may respond better to treatment with the new Alzheimer’s disease drug donanemab, according to an October 25 news report in the journal Practical Neurology. Research suggests that the accumulation of these proteins is a continuous process that starts decades before the onset of symptoms.

Disease 119
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Research Showing Genomics- and Image-Guided Subtyping Refines Characterization of Alzheimer’s Disease Presented at SNMMI 2023

Imaging Technology

Based on a novel clustering framework using sparse canonical correlation analysis (SCCA), the integrated approach was successful in identifying four subtypes of Alzheimer’s disease and the top genes associated with each, according to the authors of the study, “An SCCA-clustering framework for Alzheimer’s disease subtyping using tau PET and genomics.”

Disease 97
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FAPI-PET/CT outperforms FDG-PET/CT in women with invasive breast cancer

AuntMinnie

PET/CT imaging using gallium-68 (Ga-68) Fibroblast activation protein inhibitor (FAPI) radiotracer over F-18 FDG appears promising in women with invasive lobular carcinoma (ILC), according to a study published March 14 in the Journal of Nuclear Medicine. Image courtesy of the Journal of Nuclear Medicine.

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Types of Nuclear Medicine

Independent Imaging

Nuclear medicine is a form of specialty medicine that uses radioactive tracers to evaluate bodily functions and to diagnose and treat a wide range of health conditions. Nuclear scans produce images of the body’s anatomy that cannot be obtained as clearly or fully with other imaging techniques.

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PET reveals ‘smoldering’ brain inflammation in patients treated for MS

AuntMinnie

PET brain scans show persistent brain inflammation in patients with multiple sclerosis (MS), despite being treated with high-efficacy disease-modifying therapies, according to a recent study by researchers in Boston. Image courtesy of Clinical Nuclear Medicine. The full article is available here.

PET Scan 122
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Intraarterial PRRT safe in patients with meningioma

AuntMinnie

Intraarterial peptide receptor radionuclide therapy (PRRT) is a safe and effective alternative to intravenous PRRT in patients with advanced meningioma, according to a study published October 24 in the Journal of Nuclear Medicine. One of 10 had complete remission, one of 10 had partial remission, and eight of 10 had stable disease.