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Amyloid PET scans improve outcomes in AD patients

AuntMinnie

Alzheimer’s disease patients with cognitive impairment or dementia who were referred for amyloid PET scans had fewer hospitalizations compared with a matched control group, according to a study published October 9 in JAMA Neurology. Each participant was matched to a control Medicare beneficiary who had not undergone amyloid PET.

PET Scan 111
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PET Scans Reveal ‘smoldering’ Inflammation in patients with Multiple sclerosis

Imaging Technology

The findings were published in Clinical Nuclear Medicine. Microglia are immune cells in the brain that are thought to have a role in MS disease progression but cannot be seen by a routine MRI. The team developed a technique called F18 PBR 06 PET imaging.

PET Scan 102
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PET scan times can be reduced in Alzheimer’s patients

AuntMinnie

F-18 florbetaben PET scans for diagnosing Alzheimer’s disease can be reduced from 20 minutes to five minutes without losing accuracy, according to a recent study. Our findings suggest that shorter scan times are a viable and effective option for brain amyloid PET imaging in clinical settings,” the group wrote.

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PET reveals patient responses to new Alzheimer’s disease drug

AuntMinnie

Patients with less tau pathology on PET scans may respond better to treatment with the new Alzheimer’s disease drug donanemab, according to an October 25 news report in the journal Practical Neurology. Donanemab is a monoclonal antibody designed to bind to beta-amyloid protein that already has formed into plaque deposits.

Disease 119
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NIH highlights PET study in Parkinson’s disease

AuntMinnie

National Institutes of Health (NIH) has highlighted a study that shows cardiac PET scans can help identify people at risk for Parkinson’s disease and Lewy body dementia. Significantly, the research supports a “body first” progression model for the diseases, the researchers suggested. “We

Disease 114
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PET links impaired sleep in Alzheimer’s disease patients to tau protein

AuntMinnie

PET scans have revealed specific brain pathology that may drive sleep disturbances in Alzheimer’s disease patients, according to a study published February 8 in the Journal of the Neurological Sciences. Of these, 119 (43%) had normal cognition, 132 (24%) had mild cognitive impairment, and three (2%) had Alzheimer’s disease.

Disease 110
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FDA approves donanemab for Alzheimer's disease

AuntMinnie

Food and Drug Administration (FDA) has approved Eli Lilly's drug donanemab (Kisunla) for the treatment of early Alzheimer's disease, including mild cognitive impairment or mild dementia. According to clinical trials, amyloid PET scans showed that donanemab reduced amyloid plaques by up to 84% after 18 months of treatment.

Disease 98