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A PET study has revealed that women over the age of 70 who took menopausal hormone therapy (HT) more than a decade before have faster brain tau accumulation -- a key indicator of Alzheimers disease. The findings may inform [Alzheimers disease] risk discussions relating to womens reproductive health and treatment, the group wrote.
A PET radiotracer that detects clear-cell renal cell carcinoma proved safe and effective in a clinical trial conducted at 36 research hospitals across nine countries, according to a study published September 10 in the Lancet Oncology. The full study is available here.
AI imaging firm Brainomix has entered into a partnership with German pharmaceutical company Boehringer Ingelheim to improve the care of U.S. patients with fibrosing lung disease. Food and Drug Administration (FDA), to U.S. pulmonology centers and their networks of referring sites.
Enigma Biomedical Group USA (EBG-USA) has signed an exclusive agreement to commercialize AbbVie’s tau PET imaging biomarkers for use in patients with suspected neurodegenerative disease. If the evaluations are favorable, EBG-USA has the option to negotiate an exclusive license agreement with AbbVie for the PET ligands.
Food and Drug Administration (FDA) has granted Clarity Pharmaceuticals fast-track designation for its copper-64 (Cu-64) sarcophagine (SAR) bisPSMA radiopharmaceutical.
It’s also primed to revolutionize the pharmaceutical industry. Pharma companies that truly embrace AI can run parallel clinical trials for the same drug as a single agent or in combinations targeting multiple diseases where the drug is predicted to work. Many pharma companies have changed their CEOs at least once.
Administration of the therapeutic dose took place as part of an ongoing Phase I/IIa theranostic clinical trial conducted by Clarity Pharmaceuticals to investigate the safety and efficacy of Cu-67 SARTATE in pediatric patients with high-risk neuroblastoma.
For those unfamiliar with steatotic liver disease, this is important because Rezdiffra is the first approved treatment for MASH, which if left untreated can progress to cirrhosis, require liver transplantation, and potentially cause death. Rajarshi Banerjee, MD, PhD.
"Somebody on the other end of the spectrum might say a theranostics center represents a clinical practice where patients are administered a radiopharmaceutical, with any diagnostic imaging sent out to those who do diagnostic imaging, and then these patients are sent back for clinical care to their medical oncologist for all follow-up," he added.
Currently, when treating metastatic breast cancer patients, oncologists base clinical decisions on diagnostic tools including biopsy results which only represent the sampled area of the tumor. GE HealthCare’s Cerianna , available in the U.S., is the only FDA approved FES PET imaging agent. In the U.S.,
Imagine going in for a diagnostic MRI scan and coming out with a progressive, irreversible, and potentially fatal disease. It certainly doesn't help matters that the disease has been linked to gadolinium-based contrast agents, a ubiquitous tool in the MR armamentarium. In 2006 the U.S. report of NSF in 33 dialysis patients at a St.
milla1cf Fri, 06/21/2024 - 20:24 June 21, 2024 — GE HealthCare , a leading global medical technology, pharmaceutical diagnostics, and digital solutions innovator, and MediView XR Inc., Proceduralists must refer to standard of care imaging and prioritize clinical experience and/or judgment when using the OmnifyXR system.
The research will produce technical feedback to assist GEHC in assessing the system’s reconstruction methods, image presentation workflow, and clinical benefits for specific pathologies and disease types. MRI GEHC unveiled Signa Champion, a 1.5-tesla,
Radiologists in Ukraine have shared stories on their experiences, from living in the basement of their respective clinics to treat patients while evading bombings, to adjusting their workflows to continue delivering care. One radiologist based in Ukraine shared her perspective on the current state of medical imaging in Ukraine.
The project is the second funded and supported by NEURii, a global collaboration between the pharmaceutical company Eisai, Gates Ventures, the University of Edinburgh, the medical research charity LifeArc and the national health data science institute Health Data Research UK.
For many, machine learning's potential is more than just talk; the power of well-trained, image-augmented AI has already been demonstrated as a useful tool for quality control, disease tracking, tumor segmentation, and making prognosis predictions.
a clinical-stage biotech developing groundbreaking secretome therapeutics for age and disease-related immune dysfunction, has announced a partnership with Springbok Analytics , a life sciences muscle analytics company. christine.book Thu, 07/25/2024 - 12:44 July 25, 2024 — Immunis, Inc. ,
Ballakur added, “It gives them the features they need to scale their use of AI-enabled pathology and capitalize on the latest innovations that shape our understanding of disease.” Additionally, the company’s written statement noted that Proscia has grown its clinical customer base by more than 100% in the past year.
Curadh), a global MTR focused clinical, research and advisory organization, announced the signing of a strategic long term supply agreement for the therapeutic radioisotope non-carrier added (n.c.a.) Ac-225 and copper-67 (Cu-67) for advancing clinical research and commercial radiopharmaceutical therapy products.
announced the acquisition’s close and addition of MIM Software’s imaging analytics and digital workflow solutions as a part of its leading global medical technology, pharmaceutical diagnostics, and digital portfolio. This includes continuing to grow MIM Software’s offerings for end-to-end standardization across large healthcare system fleets.
NeuroShield is currently in clinical use in over 220+ sites across the world. NeuroShield takes 3D MR images as inputs and automatically calculates brain volumes that can assist physicians in devising treatment plans for patients with neurodegenerative diseases such as Dementia, Alzheimer's' Disease, Parkinson's, and Epilepsy.
Nucleus will use NorthStar’s Ac-225 for their customers’ radioligand pharmaceutical programs. Clinical research and commercial use of Ac-225 have been constrained by chronic short supply due to limitations of current production technology. Under terms of the agreement, NorthStar will supply its high purity, non-carrier added (n.c.a.)
The digital pathology solution was cleared for the purpose of primary diagnosis, reported the company, adding that it is cleared (K230839) for clinical use with the Hamamatsu NanoZoomer S360MD Slide scanner in the United States. Up to 70% of clinical decisions depend on pathology 1. Reference: 1. NHS England (2017).
RTX-1363S has the potential to transform the way we detect and monitor various epithelial-derived cancers." "We are delighted by our collaboration with Ratio Therapeutics in advancing the clinical development of RTX-1363S as a FAP-targeted diagnostic to the clinic," stated Etienne Montagut , Lantheus' Chief Business Officer. "By
The companies will work together to increase near-term production of 225Ac [1] to support ongoing clinical trials and to ensure the large-scale supply of the radioisotope in the long term, addressing growing global demand. Whilst there is high demand, there is a scarcity of 225Ac.
The recommendation was issued by the Pharmacovigilance Risk Assessment Committee (PRAC) of the European Medicines Agency (EMA), the primary body in the European Union responsible for regulating pharmaceuticals. The PRAC noted that no clinicaldiseases or even symptoms have been reported in connection with gadolinium deposition.
The statement further noted that digital pathology is modernizing the microscope-based practice, driving a shift to high-resolution images that each contain over 1 billion pixels telling the story of a patient’s disease.
Recognizing the industry transformation taking place as digital innovation reshapes the experience of patients and providers, GE HealthCare – a leading global medical technology, pharmaceutical diagnostics, and digital innovator – is focused on developing smart devices, aligned to disease states and enabled by digital.
This unit will enable us to develop and manufacture patient doses for pharmaceutical or biotechnology companies as well as share our radiopharmaceutical development and commercialization expertise with them where they may require additional infrastructure, resources or the specialized knowledge required for complex radiopharmaceutical development.
We are delighted by our collaboration with Ratio Therapeutics in advancing the clinical development of RTX-1363S as a FAP-targeted diagnostic to the clinic," stated Etienne Montagut, Lantheus' Chief Business Officer. "By milla1cf Tue, 07/11/2023 - 09:02 July 11, 2023 — Ratio Therapeutics Inc.
PMID: 34697777 Clinical Question: In patients with moderate to severe alcohol withdrawal being discharged from the emergency department (ED), does treatment with phenobarbital alone and phenobarbital plus benzodiazepines compared to benzodiazepines alone decrease the odds of returning to the ED within 3 days after initial discharge?
26, 2024 — Data scientists and clinical researchers will use brain scans from the entire Scottish population to build a software tool that they hope will help predict a person’s risk of dementia. tim.hodson Mon, 08/26/2024 - 16:49 Aug. million images.
The rise of precision medicine is putting new pressures on diagnostic laboratories to tap into their pathology data, as whole slide images are among the best representations of disease. Concentriq is used by 14 of the top 20 pharmaceutical companies and major diagnostic laboratories worldwide.
The results also follow those of the PICTURE clinical trial published in Investigative Radiology in May, 2023, which found the non-inferior quality of morphologic assessment of lesions of the brain and spine with VUEWAY compared with Gadavist. mmol/kg versus a full dose of gadobutrol (0.1 mmol/kg). [i] mmol/kg gadopiclenol (VUEWAY) with 0.1
milla1cf Fri, 01/05/2024 - 11:32 January 5, 2024 — NorthStar Medical Radioisotopes, LLC , a global innovator in development, production and commercialization of radiopharmaceuticals used to detect and treat cancer and other serious diseases, and Curadh MTR Inc.
Different types of medical imaging response criteria: morphological measures In oncology clinical trials, therapy is generally assessed using imaging response criteria involving imaging biomarkers. criteria, and therefore is the most used metric to assess efficacy in oncology clinical trials for solid tumors. The basis of RECIST1.1
Experts have long explored computer algorithms meant to improve healthcare, with some having been shown to make valuable clinical predictions. The tool also successfully assessed the likelihood of additional conditions accompanying a primary disease (comorbidity index) as well as the chances of an insurance denial.
Clinical Question: Is IV cetirizine noninferior to IV diphenhydramine for the treatment of acute urticaria? PMID: 32653333 What They Did Multi-center, double-blind, randomized, phase 3 clinical trial with a parallel-group, active-controlled, non-inferiority design. Another pharmaceutical company, Wesley Enterprise Inc.,
Cardiovascular care has seen remarkable advancements over the decades, from innovative surgical techniques to cutting-edge pharmaceuticals. Bhatt highlighted the need for inclusivity, particularly in population health, where AI can play a crucial role in identifying at-risk groups and preventing cardiovascular disease.
Technological and pharmaceutical breakthroughs. Promising clinical trials. A group of cardiologists from Cleveland Clinic and Stanford University further tested the chatbot by feeding it questions about preventative cardiology and cardiovascular disease. Solutions to combat provider labor shortages. New treatment paths.
Government hospitals face unique challenges that restrict the quality of healthcare provided thus, people prefer private hospitals and clinics. Also, the new online pharmaceutical retail industry is gradually penetrating the market. MRI scans offer many applications in the disease diagnosis like neuroscans, liver scans and cardiac.
This extraordinary circumstance increased the need for skilled healthcare professionals (particularly those experienced in critical care and disease management). The BLS report attributes this growth to both an aging population and a higher prevalence of heart disease, diabetes, cancer, and other chronic conditions.
A regular supply chain of affordable medicines and pharmaceuticals is also not in place because of limited indigenous production of drugs and scarce medical research facilities. According to the World Health Organization (WHO), Africa carries 25% of the world’s disease burden but its share of global health expenditures is less than 1%.
PMID: 32622394 Clinical Question: Can ambulatory management of patients with primary spontaneous pneumothorax reduce the length of hospitalization? Patients were observed for 1-2 hours for clinical stability, and placement was confirmed with a chest x-ray. Paper: Hallifax RJ et al. 2020;396(10243):39-49. Arch Intern Med 154: 157–163.
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