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Amyloid PET scans improve outcomes in AD patients

AuntMinnie

Alzheimer’s disease patients with cognitive impairment or dementia who were referred for amyloid PET scans had fewer hospitalizations compared with a matched control group, according to a study published October 9 in JAMA Neurology. The percentage of patients impacted was small – just 4.5%

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PET reveals ‘smoldering’ brain inflammation in patients treated for MS

AuntMinnie

The finding suggests that PET imaging of translocator protein (TSPO) in the brain can serve as a biomarker for evaluating patients whose disease progresses despite treatment, noted lead author Tarun Singhal, MD, of Brigham and Women’s Hospital and colleagues. Image courtesy of Clinical Nuclear Medicine.

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Researchers offer hypothesis for long COVID brain fog

AuntMinnie

A group in France has offered an explanation for long COVID brain fog, with the concept based on a visual brain pattern they discovered on patient PET scans, according to a study published October 13 in Medical Hypotheses. “We A) PET scan of a healthy subject. (B) B) PET scan of a long COVID patient.

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Evidence grows for use of amyloid PET in China

AuntMinnie

Chinese clinicians have provided evidence in a “real-world study” that shows amyloid PET imaging is effective for diagnosing and managing patients with Alzheimer’s disease, according to a study published February 8 in Alzheimer’s and Dementia. The clinical utility of amyloid PET scans has been systematically studied in many other countries.

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Hormone therapy linked to tau accumulation in older women

AuntMinnie

The finding could help explain why Alzheimers disease predominates in women almost twofold over men, noted lead author Gillian Coughlan, PhD, a neurologist at Massachusetts General Hospital in Boston, and colleagues. The group analyzed flortaucipir (Tauvid, Avid Pharmaceuticals) PET scans acquired over a 3.5-year

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PET reveals brain pathology that may drive depression

AuntMinnie

Early brain accumulation of amyloid plaque on PET scans is associated with emerging depressive symptoms in cognitively unimpaired older adults, according to a study published August 29 in JAMA Network Open. The mean follow-up period was 8.6 The full study is available here.

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FAPI-PET shows promise in patients with lung cancer

AuntMinnie

FAPI-PET imaging could emerge as a new tool for assessing patients with single pulmonary tumors, especially in those with negative results on other scans, according to a study published April 11 in the Journal of Nuclear Medicine. FAPI-PET either confirmed or ruled out the disease in all cases, the group found. “Our