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Radiopharmaceutical biotech firm Isotope Technologies Munich (ITM) has appointed Celine Wilke, MD, as its chief medical officer. ITM-11 is currently under investigation in a phase III clinical trial (COMPETE). Wilke specializes in clinical pharmacology and oncology and has nearly 20 years of industry experience.
Middlebrooks, MD, Mayo Clinic, Jacksonville, FL Erik H. Middlebrooks, MD, of the Mayo Clinic in Jacksonville, FL. His lab team is currently focused on "implementing advanced techniques, such as parallel transmit, to achieve more consistent image quality and fully harness the power of 7T for every patient," Middlebrooks said.
GE HealthCare has purchased full ownership of Japanese radiopharmaceutical developer Nihon Medi-Physics (NMP) from Sumitomo Chemical. NMP also provides research and development, including nonclinical and clinical development of radiotracers and theranostics research.
TerraPower recently shipped its first batch ofAc-225 through the project, and boasts more than 10 supply agreements with radiopharmaceutical developers in the U.S., So, if you do that math, it's about 90,000 millicuries per year that we would expect to be harvesting once our supply chain is at scale, he said. Canada, Australia, and in Europe.
Three clinical issues that may arise with theranostics treatments will require special provisions, including spot imaging, according to insights shared during the 124th annual meeting of the American Roentgen Ray Society (ARRS) in Boston. Spot imaging revealed that more than half of the administered activity was in the patient's arm.
Life Molecular Imaging (LMI) and Sofie Biosciences have begun offering the Neuraceq ( florbetaben F-18) PET radiotracer produced at Sofie's radiopharmaceutical manufacturing site in Cleveland, Ohio. With this expansion, LMI continues driving commercial sales of Neuraceq around the U.S.
Actinium will continue developing its lead radiopharmaceutical product Actimab-A, as well as additional early and late-stage development candidates for both U.S. and international clinical trials. Demand for Ac-225 is driven in part by the rapid development of theranostic "pairs" used in imaging and therapy.
The use of somatostatin receptor PET imaging and therapy in meningiomas is on the rise, and new guidelines on their use can help pave the way to improved outcomes for patients, experts noted in a recent article. In the U.S.,
Organizing pneumonia can hide underlying lung cancers in up to 10% of cases, and repeat imaging in the form of PET/CT -- and additional biopsy -- should be considered in patients with high clinical suspicion of malignancy, researchers have reported. The bottom line?
The new horizons of advanced imaging, especially in oncology, must increasingly consider not only diagnostic efficacy but also sustainability for patients, prize-winning researchers told ECR 2025 delegates. To mitigate these effects, low-energy imaging techniques should be prioritized without compromising diagnostic accuracy.
A radiopharmaceutical therapy that lengthens progression-free survival for patients with neuroendocrine cancer could help treat meningioma sufferers, according to research presented at the American Society for Radiation Oncology (ASTRO) meeting. Nearly 80% of patients in our study were progression-free after six months," he said.
Flyrcadois a unit-dose PET myocardial perfusion imaging (MPI) agent intended for patients with known or suspected coronary artery disease. Pass-through payment status will allow the CMS to provide separate payments for the radiopharmaceutical and the PET-CT scan when performed with Flyrcado in the hospital outpatient setting.
As nuclear medicine therapies gain stature compared to nuclear medicine in diagnostic imaging, hospital administrators may be eyeing the potential of adding theranostics services. Beyder led a theranostics practice management and logistics track at the recent Society of Nuclear Medicine and Molecular Imaging (SNMMI) annual meeting in Toronto.
With therapeutic radiopharmaceuticals coming to market quickly and available to smaller institutions around the U.S., Siegel told AuntMinnie.com. "My vision of a theranostic center includes a flagship facility that has a PET/CT scanner, a SPECT/CT scanner, and then multiple rooms for infusions of radiopharmaceuticals," Siegel explained.
Most Influential Radiology Researcher Erik Middlebrooks, MD, Mayo Clinic, Jacksonville, FL Erik Middlebrooks, MD. One of this year's nominations for Most Influential Radiology Researcher is Erik Middlebrooks, MD, of the Mayo Clinic in Jacksonville, FL. There's a huge role for AI in image acquisition," he said.
announced that it has entered into a patent license agreement with Mayo Clinic for the rights to the PSMA Alpha-PET DoubLET platform technology for the treatment of PSMA-expressing cancers, with an initial focus on prostate. milla1cf Fri, 01/05/2024 - 11:21 January 5, 2024 — Perspective Therapeutics, Inc.
Nuclidium has begun a phase I clinical trial evaluating the use of copper-61 (Cu-61) in patients with prostate-specific membrane antigen (PSMA)-positive prostate cancer. The radiopharmaceutical is called Cu-61 NuriPro and is part of the company's NuriPro program, it said. Cu-61 NuriPro has a 3.3-hour
TORONTO – The radiopharmaceutical Pluvicto improves progression-free survival in patients with metastatic prostate cancer who haven’t undergone taxane therapy, according to research presented at the SNMMI meeting. Oliver Sartor, MD The study, which was awarded SNMMI’s Abstract of the Year award, shared data from the phase III PSMAfore trial.
PET/CT is poised to become a key tool for imaging the coronary arteries – a clinicalimaging exam that can reveal early warning signs of fatal conditions when patients present with symptoms of chest pain, experts say. The game-changer could be the pending U.S. approval of new PET radiotracers, such as F-18 flurpiridaz , he said.
An open-source AI tool can help predict renal function decline in prostate cancer patients undergoing lutetium-177 (Lu-177) radiopharmaceutical therapy, according to a study published February 25 in Radiology. Image and caption courtesy of RSNA. In total, 363 CT studies were included, comprising 121 baseline and 242 follow-up scans.
a clinical stage radiopharmaceutical company focused on the discovery and development of novel agents for the treatment of a wide range of oncology indications, is pleased to announce that the first subject has been dosed in its Phase 1 study of 68Ga-R8760.
Food and Drug Administration's (FDA) approvals of radiopharmaceuticals for neuroendocrine tumors and then for prostate cancer, theranostics has picked up momentum in clinical practice, propelled by encouraging research. Since 2013 we've had several more radiopharmaceutical therapies get FDA approval.
F-18 fluorocholine (FCH) PET/CT could be a first-line technique over technetium-99m sestamibi (Tc-99m MIBI) SPECT/CT for imaging parathyroid tumors prior to surgery, according to a study published June 20 in JAMA Otolaryngology-Head & Neck Surgery. No complications occurred. The full study is available here.
milla1cf Fri, 05/10/2024 - 08:08 May 10, 2024 — Mariana Oncology , a fully integrated biotechnology company pioneering a new era of radiopharmaceutical innovation to treat people with cancer , today announced it will be acquired by Novartis for $1 billion upfront and up to $750 million in potential milestone payments.
The ubiquitous expression of FAP in cancer-associated fibroblasts across nearly all epithelial-derived cancers paired with the low abundance in normal tissues, makes it a unique target to exploit for tumor imaging for a wide variety of cancers such as breast, pancreatic, lung and stomach cancer.
Read more on AuntMinnie.com Related Reading: Blue Earth touts clinical results Blue Earth highlights results from PET tracer trial PET tracer shows promise in imaging of brain tumors Blue Earth touts PSMA radiotracer study Blue Earth moves toward U.K. prostate radiopharmaceutical licensing
an investigational radiohybrid (rh) Prostate-Specific Membrane Antigen-targeted therapeutic radiopharmaceutical, is the lead candidate in Blue Earth Therapeutics’ oncology development program of next generation therapeutic radiopharmaceuticals. Our ongoing Phase 1/2 clinical trial ( NCT05413850 ) is evaluating 177Lu-rhPSMA-10.1
The following is the list of candidates for the 2024 edition of the Minnies, AuntMinnie.com 's campaign to recognize the best and brightest in medical imaging. Image from Martin W. Image from Denis Le Bihan, PhD, of the NeuroSpin research facility, et al. Image from Richard Carson, PhD, of Yale University, et al.
The clinical trial will use this investigational radiopharmaceutical to help understand if patients have CD8+ T cells in their tumors and will, therefore, be more likely to respond to immune checkpoint inhibitors, the main class of immunotherapies currently approved for use.
The ubiquitous expression of FAP in cancer-associated fibroblasts across nearly all epithelial-derived cancers paired with the low abundance in normal tissues, makes it a unique target to exploit for tumor imaging for a wide variety of cancers such as breast, pancreatic, lung and stomach cancer.
a therapeutic oncology company and 3B Pharmaceuticals (3BP) GmbH, a biotechnology company developing targeted radiopharmaceutical drugs and diagnostics for cancer detection and treatment, announced an exclusive licensing agreement for RefleXion to develop and commercialize a specific 3BP molecule to direct its SCINTIX biology-guided radiotherapy.
and Blue Earth Diagnostics, a Bracco company and recognized leader in the development and commercialization of innovative PET radiopharmaceuticals, today provided additional information regarding a March 2022 licensing and collaboration agreement between Philochem and Blue Earth Diagnostics. Chief Executive Officer of Blue Earth Diagnostics.
In 2003, the Center for Molecular and Functional Imaging (CMFI) at China Basin Landing opened its doors with San Francisco’s first 3T MRI and two 1.5T clinical scanners, followed a few years later by a cyclotron which launched our in-house radiopharmaceutical program.
“The ROCR Act will increase access to lifesaving cancer treatments, incentivize high-value care, address disparities that undermine patient outcomes and provide a path to financial stability for radiation oncology clinics,” according to an ASTRO statement.
Chinese clinicians have provided evidence in a “real-world study” that shows amyloid PET imaging is effective for diagnosing and managing patients with Alzheimer’s disease, according to a study published February 8 in Alzheimer’s and Dementia. The clinical utility of amyloid PET scans has been systematically studied in many other countries.
30, 2025 Earlier this month, the Society of Nuclear Medicine and Molecular Imaging (SNMMI) and the Alzheimers Association released updated appropriate use criteria (AUC) for amyloid and tau PET imaging in patients with mild cognitive impairment, Alzheimers disease and other dementias. tim.hodson Thu, 01/30/2025 - 10:20 Jan.30,
NorthStar Medical Radioisotopes has completed a cleanroom facility at its campus in Beloit, WI, to support batch production of radiopharmaceuticals for research and treatment. The cleanroom at NorthStar's campus in Beloit, WI.
milla1cf Fri, 09/08/2023 - 16:25 September 8, 2023 — Positron Corporation , a leading molecular imaging medical device company, is pleased to announce that the Company will begin its clinical study of its Affinity PET-CT imaging device with Ochsner Clinic Foundation in New Orleans, LA. on September 18, 2023.
milla1cf Wed, 02/21/2024 - 18:58 February 21, 2024 — Blue Earth Therapeutics , a Bracco company and emerging leader in the development of innovative next generation therapeutic radiopharmaceuticals, is pleased to share the publication of promising early clinical data with 177Lu-rhPSMA-10.1 177Lu-rhPSMA-10.1 177Lu-rhPSMA-10.1
Flyrcadois a unit-dose PET myocardial perfusion imaging (MPI) agent intended for patients with known or suspected coronary artery disease. Pass-through payment status will allow the CMS to provide separate payments for the radiopharmaceutical and the PET-CT scan when performed with Flyrcado in the hospital outpatient setting.
Voximetry now offers nuclear medicine dosimetry technology as a remote service, with its recent launch of RPT Dosimetry Clinical Services. Incorporating radiopharmaceutical therapy dosimetry typically requires advanced, in-house software, and a trained physics staff, Voximetry said.
The Care Innovation Hub leverages the strengths of academia and industry to create, evaluate and translate novel technology into a clinical setting with the goals of advancing diagnosis and treatment of disease, improving hospital operations and driving more equitable access to care. tim.hodson Mon, 01/27/2025 - 10:11 Jan.
A decade ago, only a few radiopharmaceutical agents were used to help treat cancer patients. Even if some private urology, radiation oncology practices, or radiologist groups are building the ability to perform theranostics, experts are cautious about patient management, radiation safety, and the risk of unnecessary imaging.
Read more on AuntMinnie.com Related Reading: FDA approves new PET tracer for prostate cancer imaging Blue Earth touts clinical results PET tracer shows promise in imaging of brain tumors Blue Earth touts PSMA radiotracer study Blue Earth moves toward U.K. prostate radiopharmaceutical licensing
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