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PET Scans Reveal ‘smoldering’ Inflammation in patients with Multiple sclerosis

Imaging Technology

The findings were published in Clinical Nuclear Medicine. The newly published study involved performing PET scans on 22 people with MS and eight healthy controls. Those being treated with low-efficacy treatments had more abnormalities on their PET scans, suggesting more microglial cell activation.

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PET reveals ‘smoldering’ brain inflammation in patients treated for MS

AuntMinnie

In a study published April 17 in Clinical Nuclear Medicine , the group at Brigham tested a new TSPO radiotracer they developed for visualizing such activity called F-18 PBR06. The researchers performed F-18 PBR06 PET scans on 22 patients with MS and eight healthy controls.

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PET sheds light on opioid addiction treatments

AuntMinnie

PET imaging shows different brain activity in people taking methadone or buprenorphine for opioid use disorder (OUD), according to a presentation at the recent Society of Nuclear Medicine and Molecular Imaging annual meeting. They tracked serum levels of methadone or buprenorphine for the OUD subjects.

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The rise of theranostics: Part 1 -- Gaining momentum

AuntMinnie

Food and Drug Administration's (FDA) approvals of radiopharmaceuticals for neuroendocrine tumors and then for prostate cancer, theranostics has picked up momentum in clinical practice, propelled by encouraging research. The nuclear radiologist, nuclear medicine technologist, and radiation safety team are all present to administer an infusion.

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New PET Tracer Detects Inflammatory Arthritis Before Symptoms Appear

Imaging Technology

milla1cf Fri, 02/09/2024 - 09:17 February 9, 2024 — A novel PET imaging technique can noninvasively detect active inflammation in the body before clinical symptoms arise, according to research published in the February issue of The Journal of Nuclear Medicine.

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PET lung scan times could be cut by half

AuntMinnie

Dynamic PET scans acquired in half the time of normal scans appear clinically feasible for patients with lung lesions, according to nuclear medicine researchers in Shenzhen, China. A 60-year-old male patient with clinical suspicion of lung cancer. The article was published March 5 in EJNMMI Physics.

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PET reveals patient responses to new Alzheimer’s disease drug

AuntMinnie

Patients with less tau pathology on PET scans may respond better to treatment with the new Alzheimer’s disease drug donanemab, according to an October 25 news report in the journal Practical Neurology. Research suggests that the accumulation of these proteins is a continuous process that starts decades before the onset of symptoms.

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