AuntMinnie

APRIL 29, 2024

In a study published April 17 in Clinical Nuclear Medicine , the group at Brigham tested a new TSPO radiotracer they developed for visualizing such activity called F-18 PBR06. The researchers performed F-18 PBR06 PET scans on 22 patients with MS and eight healthy controls. Image courtesy of Clinical Nuclear Medicine.

PET Scan 306

PET Scan Nuclear Medicine Disease Clinic 306

AuntMinnie

OCTOBER 27, 2023

Patients with less tau pathology on PET scans may respond better to treatment with the new Alzheimer’s disease drug donanemab, according to an October 25 news report in the journal Practical Neurology. Research suggests that the accumulation of these proteins is a continuous process that starts decades before the onset of symptoms.

Disease 298

Disease PET Scan Clinic Diagnose 298

AuntMinnie

FEBRUARY 12, 2024

Chinese clinicians have provided evidence in a “real-world study” that shows amyloid PET imaging is effective for diagnosing and managing patients with Alzheimer’s disease, according to a study published February 8 in Alzheimer’s and Dementia. The clinical utility of amyloid PET scans has been systematically studied in many other countries.

PET Scan 262

PET Scan Diagnose Disease Radiopharmaceuticals 262

AuntMinnie

OCTOBER 18, 2023

A group in France has offered an explanation for long COVID brain fog, with the concept based on a visual brain pattern they discovered on patient PET scans, according to a study published October 13 in Medical Hypotheses. “We A) PET scan of a healthy subject. (B) B) PET scan of a long COVID patient.

PET Scan 363

PET Scan Nuclear Medicine Imaging Hospital 363

AuntMinnie

JUNE 19, 2024

Jacob Dubroff, MD, PhD, of the University of Pennsylvania in Philadelphia, provided evidence using carbon-11 (C-11) carfentanil PET that individual buprenorphine-treated patients have lower mu-opioid receptor activity across all brain regions than either methadone-treated patients or healthy controls.

PET Scan 312

PET Scan Nuclear Medicine Imaging Clinic 312

AuntMinnie

FEBRUARY 13, 2024

PET scans have revealed specific brain pathology that may drive sleep disturbances in Alzheimer’s disease patients, according to a study published February 8 in the Journal of the Neurological Sciences. Nonetheless, the results have several implications for clinical practice, they wrote.

Disease 277

Disease PET Scan Medical Clinic 277

Imaging Technology

APRIL 24, 2024

The findings were published in Clinical Nuclear Medicine. The newly published study involved performing PET scans on 22 people with MS and eight healthy controls. Those being treated with low-efficacy treatments had more abnormalities on their PET scans, suggesting more microglial cell activation.

PET Scan 102

PET Scan Disease Nuclear Medicine Clinic 102

AuntMinnie

AUGUST 29, 2024

Early brain accumulation of amyloid plaque on PET scans is associated with emerging depressive symptoms in cognitively unimpaired older adults, according to a study published August 29 in JAMA Network Open. The mean follow-up period was 8.6 The full study is available here.

PET Scan 279

PET Scan Disease Hospital Imaging 279

AuntMinnie

JULY 2, 2024

According to clinical trials, amyloid PET scans showed that donanemab reduced amyloid plaques by up to 84% after 18 months of treatment. Donanemab is a monoclonal antibody that targets and clears beta-amyloid protein in the brain.

Disease 246

Disease PET Scan MRI Clinic 246

AuntMinnie

MARCH 7, 2025

The group analyzed flortaucipir (Tauvid, Avid Pharmaceuticals) PET scans acquired over a 3.5-year Participants were clinically unimpaired and between ages 51 and 89 at the beginning of the study. The researchers aimed to investigate whether menopausal HT use is associated with later-life tau accumulation.

Disease 163

Disease PET Scan Pharmaceutical Education 163

AuntMinnie

NOVEMBER 6, 2023

PET imaging has revealed brain pathology linked to faster clinical progression of Alzheimer’s disease in patients with ApoE4 gene variants, according to a study published November 6 in JAMA Neurology.

PET Scan 264

PET Scan Disease Clinic Imaging 264

AuntMinnie

JULY 1, 2024

In small studies, F-18 PSMA-1007 PET/CT has shown promise as a more accurate approach based on its ability to reveal prostate-specific membrane antigen (PSMA) on the surface of cancer cells. In this phase II clinical trial, the researchers sought to evaluate the approach further.

MRI 264

MRI PET Scan Nuclear Medicine Bone Scan 264

AuntMinnie

MARCH 6, 2024

Dynamic PET scans acquired in half the time of normal scans appear clinically feasible for patients with lung lesions, according to nuclear medicine researchers in Shenzhen, China. A 60-year-old male patient with clinical suspicion of lung cancer. The article was published March 5 in EJNMMI Physics.

PET Scan 285

PET Scan Nuclear Medicine Imaging Clinic 285

AuntMinnie

JANUARY 30, 2024

F-18 FDG-PET is an established approach for diagnosing inflammation based on its ability to visualize increased cellular glucose metabolism, and the researchers hypothesized that it could be useful in patients with neurosarcoidosis. In all three cases, gadolinium-enhanced MRI scans did not show abnormalities.

Diagnose 270

Diagnose PET Scan MRI Disease 270

AuntMinnie

JANUARY 10, 2024

They wrote that in their daily clinical practice, for instance, they promote voluntary coughing in dysphagic patients using a procedure called “cough‐inducing method with tartaric acid” (CiTA). In this study, the researchers evaluated whether the experimental PET system could clarify brain activity during CiTA.

PET Scan 246

PET Scan Magnetic Resonance Imaging Clinic Hospital 246

AuntMinnie

DECEMBER 18, 2023

PET scans typically used for diagnosing prostate cancer may have value in detecting inflammatory bowel disease (IBD), according to a case series published December 8 in Clinical and Experimental Gastroenterology. D) Axial F-18 DCFPyL PET/CT fusion imaging identifying active inflammation in the descending colon.

Disease 321

Disease PET Scan Diagnose Clinic 321

AuntMinnie

APRIL 15, 2024

“Our results suggest that supplemental Ga-68 FAPI-46 PET may improve the noninvasive assessment of primary pulmonary lesions compared with F-18 FDG-PET and CT alone,” wrote lead author Manuel Röhrich, MD, and colleagues. This “markedly hampers” the assessment of single pulmonary lesions, the authors wrote.

Nuclear Medicine 306

Nuclear Medicine PET Scan Hospital Clinic 306

AuntMinnie

JULY 25, 2024

The finding comes from a group at the Leuven Brain Institute in Leuven, Belgium, who compared tau PET/MRI brain scans among participants with late-life depression, mild cognitive impairment (MCI) due to Alzheimer’s disease, and nondepressed older adults.

MRI 240

MRI PET Scan Disease Diagnose 240

AuntMinnie

JANUARY 23, 2025

A better understanding of the association between depressive symptoms and amyloid pathology will strengthen clinical diagnostics and prognosis and is essential for further therapeutic research, the group wrote. The study was published January 22 in JAMA Psychiatry.

PET Scan 244

PET Scan Disease Clinic Diagnostic 244

AuntMinnie

DECEMBER 19, 2023

Clinical brain imaging with a newly developed portable PET scanner appears feasible, with a comparison to conventional PET imaging for the first time revealing similar results in human subjects, according to a group in New York City. A link to the full study can be found here.

Nuclear Medicine 306

Nuclear Medicine PET Scan Imaging Clinic 306

AuntMinnie

JUNE 30, 2024

Mayo Clinic, Jacksonville, FL MOST SIGNIFICANT NEWS EVENT IN RADIOLOGY 1. Increased use of medical imaging by other specialties (turf battles) HOTTEST CLINICAL PROCEDURE 1. Hybrid CT/PET scanning 2. Weber State University, Ogden, UT 2. Introduction of 16-slice CT scanners 2. Ongoing shortage of qualified staff 2.

Radiology Technologist 264

Radiology Technologist X-ray PET Scan Education 264

AuntMinnie

MARCH 25, 2025

One potential application of fill-state data could be to serve as a readout for clinical trials, pending proof of longitudinal efficacy, the researchers added. If these challenges are successfully addressed, fill states may become a valuable tool for the diagnosis and staging of AD in PET imaging, Yun and Kim concluded.

Diagnose 237

Diagnose Disease PET Scan Clinic 237

Imaging Technology

MAY 22, 2023

Dr. Timothy Cloughesy, professor of neuro-oncology at the David Geffen School of Medicine at UCLA, is the senior author of abstract LBA1 , which highlights INDIGO clinical trial results, a global, randomized double-blinded, phase 3 study of vorasidenib verse placebo in patients with residual or recurrent grade 2 glioma with an IDH1/2 mutation.

PET Scan 98

PET Scan Clinic 98

AuntMinnie

JANUARY 23, 2024

For instance, while the FDA advises that selection of patients for treatment be made using an approved PSMA radiotracer and based on tracer uptake in tumors, they found that most commonly, subjective visual whole-body PSMA-PET scans were performed (33%). In addition, different PET radiotracers are used.

Nuclear Medicine 246

Nuclear Medicine PET Scan Imaging Clinic 246

Future Teleradiology

NOVEMBER 30, 2023

Teleradiology & Radiology data for artificial intelligence (AI) Introduction: Embark on a journey into the world of medical imaging as we unravel the distinctions between two powerful diagnostic tools—Computed Tomography (CT) scans and Positron Emission Tomography (PET) scans.

PET Scan 52

PET Scan Computed Tomography X-ray Imaging Modalities 52

AuntMinnie

MARCH 26, 2024

Food and Drug Administration's (FDA) approvals of radiopharmaceuticals for neuroendocrine tumors and then for prostate cancer, theranostics has picked up momentum in clinical practice, propelled by encouraging research. Since the U.S. please insert video here.

Nuclear Medicine 306

Nuclear Medicine Radiopharmaceuticals Radiation Health Science 306

Diagnostic Imaging

JANUARY 25, 2024

For patients with recurrent prostate cancer, PET scanning with 18F-flotufolastat led to major changes in treatment for 80 percent of patients and 75 percent of patients with a changed treatment focus to watchful waiting had negative scans, according to new research presented at the American Society of Clinical Oncology (ASCO) Genitourinary Cancers (..)

PET Scan 91

PET Scan Imaging Clinic 91

Imaging Technology

FEBRUARY 9, 2024

milla1cf Fri, 02/09/2024 - 09:17 February 9, 2024 — A novel PET imaging technique can noninvasively detect active inflammation in the body before clinical symptoms arise, according to research published in the February issue of The Journal of Nuclear Medicine. The nonspecific control peptide demonstrated only low binding. “68

PET Scan 115

PET Scan Nuclear Medicine Disease Clinic 115

Imaging Technology

JANUARY 30, 2025

Centers for Medicare and Medicaid Services (CMS) has announced key changes to reimbursement that make advanced imaging more accessible, lifting its one-scan-per-patient restriction in 2023 and unbundling payment for high-cost diagnostic radiopharmaceuticals in 2024. Facilities wishing to appear on this list can fill out this brief survey.

Nuclear Medicine 52

Nuclear Medicine Imaging Patient Care Disease 52

MedImaging General Imaging

JUNE 30, 2023

A new technology, dubbed 'Augmented Whole-Body Scanning via Magnifying PET' (AWSM-PET), has been shown to enhance the image resolution and system sensitivity of clinical whole-body PET/CT imaging

PET Scan 52

PET Scan Imaging Clinic 52

Medical Xpress: Radiology

JULY 16, 2024

Amyloid PET scans provide in-vivo evidence of Alzheimer's disease (AD) pathology. However, due to their high cost and limited insurance coverage, they are not widely used in clinical settings outside of the VA Healthcare System.

Disease 60

Disease PET Scan Insurance Diagnostic 60

Imaging Technology

JUNE 24, 2023

mtaschetta-millane Sat, 06/24/2023 - 15:00 June 24, 2023 — A newly developed technology called “augmented whole-body scanning via magnifying PET” ( AWSM-PET ) has been shown to enhance the image resolution and system sensitivity of clinical whole-body PET/CT imaging.

Nuclear Medicine 98

Nuclear Medicine Imaging PET Scan Diagnostic 98

Diagnostic Imaging

JULY 19, 2023

Recognizing the advent of beta amyloid-targeted therapies for the treatment of Alzheimer’s disease, the Centers for Medicare and Medicaid (CMS) has proposed eliminating coverage restrictions that limit amyloid positron emission tomography (PET) scans to clinical trial participants and one amyloid PET scan per lifetime.

Disease 52

Disease PET Scan Medicare Imaging 52

Imaging Technology

OCTOBER 19, 2023

LEADS participants receive a standard clinical evaluation and Magnetic Resonance Imaging ( MRI ) scanning as well as amyloid and tau PET scanning and fluid biomarker assessments on an annual basis. What Are the Clinical Implications? What Were Your Findings?

Disease 111

Disease MRI Magnetic Resonance Imaging PET Scan 111

Imaging Technology

SEPTEMBER 12, 2023

As one of the world’s authorities on prostate cancer treatment, Dr. Zelefsky has made major contributions to the field, shaping clinical practice guidelines and influencing treatment protocols worldwide.

Radiation 115

Radiation Radiation Oncology PET Scan Medical 115

MSK Library

MARCH 16, 2021

This can look like a clinically significant finding on cancer imaging, including chest CTs, PET scans, mammography, and breast MRI. A small but significant number of people experience swollen lymph nodes as a side effect of receiving a COVID vaccine. … Continue reading →

PET Scan 52

PET Scan Imaging MRI Clinic 52

Imaging Technology

JUNE 15, 2023

The clinical trial will use this investigational radiopharmaceutical to help understand if patients have CD8+ T cells in their tumors and will, therefore, be more likely to respond to immune checkpoint inhibitors, the main class of immunotherapies currently approved for use. Fruhwirth, G. Kneilling, M., De Vries, I. Weigelin, B.,

Radiopharmaceuticals 98

Radiopharmaceuticals Pharmaceutical Nuclear Medicine PET Scan 98