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Radiopharmaceutical biotech firm Isotope Technologies Munich (ITM) has appointed Celine Wilke, MD, as its chief medical officer. ITM-11 is currently under investigation in a phase III clinical trial (COMPETE). Wilke specializes in clinical pharmacology and oncology and has nearly 20 years of industry experience.
Nucleus RadioPharma will use the money to establish manufacturing facilities—with one located in Rochester, Minnesota, near Mayo—and build new technology for distribution.
The Swiss drugmaker said the deal will bolster its research infrastructure and clinical supply capabilities, with an eye toward improving oncologic care.
Three clinical issues that may arise with theranostics treatments will require special provisions, including spot imaging, according to insights shared during the 124th annual meeting of the American Roentgen Ray Society (ARRS) in Boston. However, using lemon juice to assess toxicity will be more practical for most clinics.
GE HealthCare has purchased full ownership of Japanese radiopharmaceutical developer Nihon Medi-Physics (NMP) from Sumitomo Chemical. NMP also provides research and development, including nonclinical and clinical development of radiotracers and theranostics research.
TerraPower recently shipped its first batch ofAc-225 through the project, and boasts more than 10 supply agreements with radiopharmaceutical developers in the U.S., So, if you do that math, it's about 90,000 millicuries per year that we would expect to be harvesting once our supply chain is at scale, he said. Canada, Australia, and in Europe.
Middlebrooks, MD, Mayo Clinic, Jacksonville, FL Erik H. Middlebrooks, MD, of the Mayo Clinic in Jacksonville, FL. Given the extensive array of sequences and techniques employed in clinical imaging, we must address the inherent challenges associated with each," he noted. Middlebrooks, MD. from Ukraine.
Actinium will continue developing its lead radiopharmaceutical product Actimab-A, as well as additional early and late-stage development candidates for both U.S. and international clinical trials.
The company has entered into asset purchase and exclusive worldwide in-license agreements for a suite of clinically validated FAP-targeting therapeutic and precision medicine radiopharmaceutical candidates.
These SSTRs can be targeted both with gallium-68 (Ga-68) imaging agents and therapeutic lutetium-177 (Lu-177) radiopharmaceuticals using a so-called theranostics approach. Meningiomas are the most common primary adult intracranial tumors and most meningiomas show high expression of somatostatin receptors (SSTRs). In the U.S.,
The analysis might help to establish a model for balancing clinical and environmental priorities in radiology departments globally. Late-phase imaging was performed when clinically indicated for liver or kidney conditions. SPECT and low-dose CT scans could be added for areas with suspected radiopharmaceutical uptake.
Pass-through payment status will allow the CMS to provide separate payments for the radiopharmaceutical and the PET-CT scan when performed with Flyrcado in the hospital outpatient setting. Flyrcado will be unveiled at the ACC conference on March 29.
Reshaping the hospital's nuclear medicine and radiopharmaceutical strategy toward theranostics involves intensive and inclusive planning, Beyder explained at SNMMI. Underwood led the nuclear medicine and radiopharmaceutical therapy team within radiation safety at Mayo Clinic and directly supports the program in Rochester.
announced that it has entered into a patent license agreement with Mayo Clinic for the rights to the PSMA Alpha-PET DoubLET platform technology for the treatment of PSMA-expressing cancers, with an initial focus on prostate. milla1cf Fri, 01/05/2024 - 11:21 January 5, 2024 — Perspective Therapeutics, Inc.
Blue Earth Diagnostics is highlighting results from a clinical study that ha. prostate radiopharmaceutical licensing Blue Earth to highlight PET study results at ASTRO Blue Earth wins FDA nod for PSMA-PET tracer NDA
Nuclidium has begun a phase I clinical trial evaluating the use of copper-61 (Cu-61) in patients with prostate-specific membrane antigen (PSMA)-positive prostate cancer. The radiopharmaceutical is called Cu-61 NuriPro and is part of the company's NuriPro program, it said.
With therapeutic radiopharmaceuticals coming to market quickly and available to smaller institutions around the U.S., My vision of a theranostic center includes a flagship facility that has a PET/CT scanner, a SPECT/CT scanner, and then multiple rooms for infusions of radiopharmaceuticals," Siegel explained.
milla1cf Fri, 05/10/2024 - 08:08 May 10, 2024 — Mariana Oncology , a fully integrated biotechnology company pioneering a new era of radiopharmaceutical innovation to treat people with cancer , today announced it will be acquired by Novartis for $1 billion upfront and up to $750 million in potential milestone payments.
TORONTO – The radiopharmaceutical Pluvicto improves progression-free survival in patients with metastatic prostate cancer who haven’t undergone taxane therapy, according to research presented at the SNMMI meeting. Oliver Sartor, MD The study, which was awarded SNMMI’s Abstract of the Year award, shared data from the phase III PSMAfore trial.
a clinical stage radiopharmaceutical company focused on the discovery and development of novel agents for the treatment of a wide range of oncology indications, is pleased to announce that the first subject has been dosed in its Phase 1 study of 68Ga-R8760. Gary Hammer , M.D.,
Most Influential Radiology Researcher Erik Middlebrooks, MD, Mayo Clinic, Jacksonville, FL Erik Middlebrooks, MD. One of this year's nominations for Most Influential Radiology Researcher is Erik Middlebrooks, MD, of the Mayo Clinic in Jacksonville, FL.
Life Molecular Imaging (LMI) and Sofie Biosciences have begun offering the Neuraceq ( florbetaben F-18) PET radiotracer produced at Sofie's radiopharmaceutical manufacturing site in Cleveland, Ohio. With this expansion, LMI continues driving commercial sales of Neuraceq around the U.S.
United Theranostics has secured $15 million in funding from Old National Bank to expand its network of radiopharmaceutical therapy clinics for cancer treatment. The new clinics will be modeled after United Theranostics' founding site in Glen Burnie, MD, and its most recently opened facility in Princeton, NJ, it said.
Organizing pneumonia can hide underlying lung cancers in up to 10% of cases, and repeat imaging in the form of PET/CT -- and additional biopsy -- should be considered in patients with high clinical suspicion of malignancy, researchers have reported. The bottom line?
a therapeutic oncology company and 3B Pharmaceuticals (3BP) GmbH, a biotechnology company developing targeted radiopharmaceutical drugs and diagnostics for cancer detection and treatment, announced an exclusive licensing agreement for RefleXion to develop and commercialize a specific 3BP molecule to direct its SCINTIX biology-guided radiotherapy.
An open-source AI tool can help predict renal function decline in prostate cancer patients undergoing lutetium-177 (Lu-177) radiopharmaceutical therapy, according to a study published February 25 in Radiology.
By leveraging our expertise in radiopharmaceuticals, we aim to contribute to the early detection and accurate monitoring of epithelial-derived cancers. This further strengthens our commitment to production and development of novel radiopharmaceuticals to advance cancer treatments and quality of life for cancer patients."
Food and Drug Administration's (FDA) approvals of radiopharmaceuticals for neuroendocrine tumors and then for prostate cancer, theranostics has picked up momentum in clinical practice, propelled by encouraging research. Since 2013 we've had several more radiopharmaceutical therapies get FDA approval. Since the U.S.
an investigational radiohybrid (rh) Prostate-Specific Membrane Antigen-targeted therapeutic radiopharmaceutical, is the lead candidate in Blue Earth Therapeutics’ oncology development program of next generation therapeutic radiopharmaceuticals. Our ongoing Phase 1/2 clinical trial ( NCT05413850 ) is evaluating 177Lu-rhPSMA-10.1
The clinical trial will use this investigational radiopharmaceutical to help understand if patients have CD8+ T cells in their tumors and will, therefore, be more likely to respond to immune checkpoint inhibitors, the main class of immunotherapies currently approved for use.
MIBI-SPECT/CT is considered the standard technique for guiding these surgeries, yet several phase II clinical trials suggest advantages of a newer approach using FCH-PET, such as superior spatial resolution for detecting small adenomas and lower radiation exposure to patients, they noted. The full study is available here.
milla1cf Wed, 02/21/2024 - 18:58 February 21, 2024 — Blue Earth Therapeutics , a Bracco company and emerging leader in the development of innovative next generation therapeutic radiopharmaceuticals, is pleased to share the publication of promising early clinical data with 177Lu-rhPSMA-10.1 177Lu-rhPSMA-10.1 177Lu-rhPSMA-10.1
Blue Earth Therapeutics is highlighting early clinical results from a German trial investigating the use of a lutetium-177 (Lu-177)-labeled prostate specific antigen (PSMA) radiopharmaceutical. A phase I and II clinical trial assessing the safety, tolerability, dosimetry, and antitumor activity of Lu-177 rhPSMA-10.1
In patients treated at a memory clinic at Huashan Hospital in Shanghai, amyloid PET scans detected brain pathology associated with the disease and led to changes in treatment plans in 36.5% The clinical utility of amyloid PET scans has been systematically studied in many other countries. The full study is available here.
The mutual aim of the collaboration is to jointly establish commercial supply chains that can be accessed by radiopharmaceutical drug developers for clinical trials and commercial applications, according to Nusano.
We are delighted by our collaboration with Ratio Therapeutics in advancing the clinical development of RTX-1363S as a FAP-targeted diagnostic to the clinic," stated Etienne Montagut, Lantheus' Chief Business Officer. "By milla1cf Tue, 07/11/2023 - 09:02 July 11, 2023 — Ratio Therapeutics Inc.
NorthStar Medical Radioisotopes has completed a cleanroom facility at its campus in Beloit, WI, to support batch production of radiopharmaceuticals for research and treatment. The cleanroom at NorthStar's campus in Beloit, WI.
Aktis Oncology has entered a potential $1 billion collaboration agreement with Eli Lilly to generate anticancer radiopharmaceuticals using its miniprotein technology platform. billion in potential preclinical, clinical, regulatory, and commercial milestones, as well as tiered royalties, it noted.
milla1cf Fri, 09/08/2023 - 16:25 September 8, 2023 — Positron Corporation , a leading molecular imaging medical device company, is pleased to announce that the Company will begin its clinical study of its Affinity PET-CT imaging device with Ochsner Clinic Foundation in New Orleans, LA. on September 18, 2023.
NorthStar Medical Radioisotopes and Chester Springs, PA-based Curadh MTR have entered a strategic collaboration agreement to develop radiopharmaceuticals for the treatment of primary and metastatic solid tumors.
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