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Pre-Hospital Antibiotics in Sepsis?

REBEL EM

PMID: 35387313 Clinical Question: Do prehospital antibiotics impact 28 day mortality, length of stay in the hospital and ICU length of stay for patients triggering sepsis compared to usual care (No prehospital antibiotics)? to 0.97; p = 0.02 to 2.07; p = 0.91 to 12.33; p = 0.26 to 0.97; p = 0.02 to 2.07; p = 0.91 to 12.33; p = 0.26

Hospital 132
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Microflow imaging useful in diagnosing breast lesions

AuntMinnie

Researchers led by Runlan Luo, MD, from the Chinese PLA General Hospital in Beijing found that this method along with high-definition microflow imaging outperforms color Doppler flow imaging in diagnosing breast lesions. High-definition microflow imaging meanwhile has been touted as an advanced version of the original method.

Diagnose 126
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ASTRO and ESTRO Issue Clinical Guideline on Local Therapy for Oligometastatic Lung Cancer

Imaging Technology

The guideline emphasizes the need for a multidisciplinary team approach to guide treatment decisions for oligometastatic disease, a description for cancer that reaches a state in which the patient has a small number of metastases in addition to a primary tumor. The guideline is published in Practical Radiation Oncology.

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MRI reveals functional brain alterations associated with depression

AuntMinnie

Those who had been identified with Hospital ICD-10 diagnosis codes F32 and F33 and antidepressant use had the most alterations in these measures. "We The team found that, across all depression criteria, study participants with lifetime depression showed consistent decreases in fALFF, LCOR, and GCOR but not in gray matter volume.

MRI 105
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Can PET help diagnose neurosarcoidosis?

AuntMinnie

To date, F-18 FDG PET findings are currently not taken into account when making a diagnosis for possible, probable, or definite neurosarcoidosis,” noted lead author Jessy Chen, MD, of Charité - Berlin University Medicine, and colleagues. The article was published January 25 in Neurological Research and Practice.

Diagnose 108
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The COVID-OUT Trial: Does Metformin Reduce the Risk of Long COVID?

REBEL EM

Our understanding of the disease and effective treatments to reduce mortality have progressed rapidly during this time. Relatively small study given the scope of the disease. This study helps to solidify the diagnosis of long COVID; for an effective therapy to exist, there must also exist a disease (see Faust editorial linked below).

Disease 145
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REBEL Cast Ep123: Reduced-Dose Systemic Peripheral Alteplase in Massive PE?

REBEL EM

in the paper but 2.7% to ≈0.99 (p<0.001) Mean MPI/Tei Index≈ 0.47 in the paper but 2.7% to ≈0.99 (p<0.001) Mean MPI/Tei Index≈ 0.47 selection bias) Unclear therapies prior to lytics (i.e.

Hospital 136