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Pre-Hospital Antibiotics in Sepsis?

REBEL EM

PMID: 35387313 Clinical Question: Do prehospital antibiotics impact 28 day mortality, length of stay in the hospital and ICU length of stay for patients triggering sepsis compared to usual care (No prehospital antibiotics)? to 0.97; p = 0.02 to 2.07; p = 0.91 to 12.33; p = 0.26 to 0.97; p = 0.02 to 2.07; p = 0.91 to 12.33; p = 0.26

Hospital 122
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Microflow imaging useful in diagnosing breast lesions

AuntMinnie

Researchers led by Runlan Luo, MD, from the Chinese PLA General Hospital in Beijing found that this method along with high-definition microflow imaging outperforms color Doppler flow imaging in diagnosing breast lesions. High-definition microflow imaging meanwhile has been touted as an advanced version of the original method.

Diagnose 122
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TAME Trial: Mild Hypercapnia vs Normocapnia in Out-of-Hospital Cardiac Arrest

REBEL EM

In response to this critical issue, the TAME Cardiac Arrest Trial has been launched as a definitive phase III multi-center randomized controlled trial for resuscitated cardiac arrest patients. Mild Hypercapnia or Normocapnia after Out-of-Hospital Cardiac Arrest. Paper: Eastwood G, et al. N Engl J Med. Epub 2023 Jun 15.

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MRI reveals functional brain alterations associated with depression

AuntMinnie

Those who had been identified with Hospital ICD-10 diagnosis codes F32 and F33 and antidepressant use had the most alterations in these measures. "We The team found that, across all depression criteria, study participants with lifetime depression showed consistent decreases in fALFF, LCOR, and GCOR but not in gray matter volume.

MRI 105
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Koneksa Announces Study with New York Proton Center to Collect Patient-Generated Health Data During Proton Radiotherapy in Lung Cancer

Imaging Technology

Locally advanced non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC) are typically treated with definitive thoracic radiotherapy (RT), often in the form of concurrent chemoradiotherapy (CRT). These adverse events often lead to hospitalizations and treatment interruptions that can reduce treatment efficacy.

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REBEL Cast Ep122 – Delayed vs Rapid Sequence Intubation in Agitated Trauma Patients

REBEL EM

Background: Getting a definitive airway in a critically ill trauma patient can be a stressful situation. PMID: 37058727 Clinical Question: Does delayed sequence intubation decrease peri-intubation hypoxia in trauma patients requiring definitive airway control compared to rapid sequence intubation? Anesth Analg 2023.

Clinic 86
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ASTRO and ESTRO Issue Clinical Guideline on Local Therapy for Oligometastatic Lung Cancer

Imaging Technology

A growing body of research, however, points to an additional role for definitive local therapy to all disease sites, aiming at durable tumor control and improved survival outcomes. Radiation and surgery are the only recommended modalities for definitive local treatment of oligometastatic NSCLC.