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PET visualizes acute graft versus host disease

AuntMinnie

F-18 fluorothymidine (FLT) PET can identify early acute gastrointestinal graft versus host disease (GVHD) after patients undergo bone marrow transplants, according to a study published December 13 in Radiology: Imaging Cancer. Blood cancers start in the cells of the immune system or in blood-forming tissue, such as the bone marrow.

Disease 279
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PSMA-PET/CT identifies 'atypical' metastases in prostate cancer patients

AuntMinnie

PET/CT scans with an experimental prostate-specific membrane antigen (PSMA) imaging agent can identify supraclavicular nodal metastasis in newly diagnosed prostate cancer patients, researchers have reported. For the analysis, the researchers included 240 patients who underwent scans for primary staging of newly diagnosed disease.

Disease 264
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MRI radiomics model predicts risk in women with DCIS

AuntMinnie

are diagnosed as DCIS, an early form of breast cancer that forms in the milk ducts, based on dynamic contrast-enhanced (DCE) MRI and biopsies. Most women undergo surgery, yet only 26% of DCIS cases are subsequently identified as invasive disease, the authors noted. About 20% of new breast cancers in the U.S.

MRI 297
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New method proposed for diagnosing Alzheimer’s

AuntMinnie

Researchers in Germany have proposed a new approach derived from brain PET imaging for diagnosing and staging Alzheimers disease, according to a study published March 25 in Radiology. Yet average SUV ratios largely ignore the spatial distribution of pathology, which can vary among individuals.

Diagnose 237
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F-18 FAPI PET/CT upstages more newly-diagnosed breast cancers

AuntMinnie

F-18 fibroblast activation protein inhibitor (FAPI) PET/CT leads to significant upstaging in newly diagnosed breast cancer, according to research published September 5 in Academic Radiology. The team put F-18 FAPI PET/CT to the test, comparing results to those of F-18 FDG PET/CT in systemic staging of newly diagnosed breast cancer.

Diagnose 306
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Benign breast disease found on percutaneous biopsy ups cancer risk

AuntMinnie

Benign breast disease diagnosed through percutaneous biopsy increases the overall risk of developing breast cancer, according to research published December 13 in JAMA Surgery. Benign breast disease makes up about 75% of breast biopsy diagnoses. The study included data from 4,819 women with a median age of 51.

Disease 306
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Bone scans may be viable for diagnosing calciphylaxis

AuntMinnie

Technetium-99m (Tc-99m) methyl diphosphonate (MDP) bone scans are a potentially viable noninvasive option for diagnosing calciphylaxis, according to a team at the University of Massachusetts in Worcester, MA. All but one patient had renal disease and most had several other comorbidities, the authors wrote.

Bone Scan 297