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Amyloid PET scans improve outcomes in AD patients

AuntMinnie

Alzheimer’s disease patients with cognitive impairment or dementia who were referred for amyloid PET scans had fewer hospitalizations compared with a matched control group, according to a study published October 9 in JAMA Neurology. The percentage of patients impacted was small – just 4.5%

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PET Scans Reveal ‘smoldering’ Inflammation in patients with Multiple sclerosis

Imaging Technology

Microglia are immune cells in the brain that are thought to have a role in MS disease progression but cannot be seen by a routine MRI. The team developed a technique called F18 PBR 06 PET imaging. The newly published study involved performing PET scans on 22 people with MS and eight healthy controls.

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PET predicts adverse events in heart disease patients

AuntMinnie

PET imaging with nitrogen-13 (N-13) ammonia radiotracer can help predict major adverse cardiac events in patients with ischemic heart disease (IHD), according to a study published May 30 in Radiology: Cardiothoracic Imaging. Patients underwent the scans between January 2017 and January 2021. The full study is available here.

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Research Spotlight: Validating an MRI Biomarker for Early Onset Alzheimer’s Disease

Imaging Technology

Is there a signature biomarker for younger/early-onset Alzheimer’s Disease (EOAD)? Sporadic early-onset Alzheimer’s disease (EOAD) is rare and understudied. The Sporadic Early-onset Alzheimer’s Disease Signature Of Atrophy: Preliminary Findings From The Longitudinal Early-onset Alzheimer’s Disease Study (LEADS) Cohort.

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PET reveals brain pathology that may drive depression

AuntMinnie

Early brain accumulation of amyloid plaque on PET scans is associated with emerging depressive symptoms in cognitively unimpaired older adults, according to a study published August 29 in JAMA Network Open. Their aim in this study was to determine whether these associations persist or progress over time.

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PET reveals ‘smoldering’ brain inflammation in patients treated for MS

AuntMinnie

PET brain scans show persistent brain inflammation in patients with multiple sclerosis (MS), despite being treated with high-efficacy disease-modifying therapies, according to a recent study by researchers in Boston. The researchers performed F-18 PBR06 PET scans on 22 patients with MS and eight healthy controls.

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Evidence grows for use of amyloid PET in China

AuntMinnie

Chinese clinicians have provided evidence in a “real-world study” that shows amyloid PET imaging is effective for diagnosing and managing patients with Alzheimer’s disease, according to a study published February 8 in Alzheimer’s and Dementia. of patients, noted lead author Ke-Liang Chen, MD, a neurologist at Fudan University. “In

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