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PET Scans Reveal ‘smoldering’ Inflammation in patients with Multiple sclerosis

Imaging Technology

Microglia are immune cells in the brain that are thought to have a role in MS disease progression but cannot be seen by a routine MRI. The team developed a technique called F18 PBR 06 PET imaging. The newly published study involved performing PET scans on 22 people with MS and eight healthy controls.

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CMS proposal covers PET scans for Alzheimer’s disease

AuntMinnie

Read more on AuntMinnie.com Related Reading: FDA grants full approval to Alzheimer's disease drug Leqembi CMS rethinks limit on PET scans for Alzheimer’s disease patients FDA doubles MRI scans needed for Aduhelm patients CMS to limit coverage of new drugs for Alzheimer's disease CMS scrubs rule restricting PET tracer coverage

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FDA approves donanemab for Alzheimer's disease

AuntMinnie

Food and Drug Administration (FDA) has approved Eli Lilly's drug donanemab (Kisunla) for the treatment of early Alzheimer's disease, including mild cognitive impairment or mild dementia. According to clinical trials, amyloid PET scans showed that donanemab reduced amyloid plaques by up to 84% after 18 months of treatment.

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Research Spotlight: Validating an MRI Biomarker for Early Onset Alzheimer’s Disease

Imaging Technology

Is there a signature biomarker for younger/early-onset Alzheimer’s Disease (EOAD)? Sporadic early-onset Alzheimer’s disease (EOAD) is rare and understudied. Sporadic early-onset Alzheimer’s disease (EOAD) is rare and understudied. What Question Were You Investigating? What Were Your Findings? Alzheimer’s Dement.

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PET/MRI rules out tau protein in late-life depression

AuntMinnie

A PET/MRI study has provided insights into the neurobiology of late-life depression, with researchers reporting that tau protein – a key protein involved in Alzheimer’s disease – does not appear to be involved in the condition. All patients were of similar ages and all were white.

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PET/MRI reveals separate Alzheimer’s biomarkers in single scan

AuntMinnie

A PET radiotracer for diagnosing Alzheimer’s disease may also be used to measure vascular brain changes in patients during PET/MRI scans, according to a study published December 7 in the Journal of Nuclear Medicine. The researchers enrolled 20 participants. Image courtesy of the Journal of Nuclear Medicine.

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PSMA-PET superior to MRI in phase II prostate cancer trial

AuntMinnie

PET/CT imaging with a new radiotracer (F-18 PSMA-1007) is superior to MRI prior to surgery in men with intermediate-risk and high-risk prostate cancer, according to a study published on July 1 in JAMA Oncology. The full study is available here.

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