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PET Scans Reveal ‘smoldering’ Inflammation in patients with Multiple sclerosis

Imaging Technology

Microglia are immune cells in the brain that are thought to have a role in MS disease progression but cannot be seen by a routine MRI. The team developed a technique called F18 PBR 06 PET imaging. The newly published study involved performing PET scans on 22 people with MS and eight healthy controls.

PET Scan 102
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CMS proposal covers PET scans for Alzheimer’s disease

AuntMinnie

Read more on AuntMinnie.com Related Reading: FDA grants full approval to Alzheimer's disease drug Leqembi CMS rethinks limit on PET scans for Alzheimer’s disease patients FDA doubles MRI scans needed for Aduhelm patients CMS to limit coverage of new drugs for Alzheimer's disease CMS scrubs rule restricting PET tracer coverage

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FDA approves donanemab for Alzheimer's disease

AuntMinnie

Food and Drug Administration (FDA) has approved Eli Lilly's drug donanemab (Kisunla) for the treatment of early Alzheimer's disease, including mild cognitive impairment or mild dementia. According to clinical trials, amyloid PET scans showed that donanemab reduced amyloid plaques by up to 84% after 18 months of treatment.

Disease 98
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Research Spotlight: Validating an MRI Biomarker for Early Onset Alzheimer’s Disease

Imaging Technology

Is there a signature biomarker for younger/early-onset Alzheimer’s Disease (EOAD)? Sporadic early-onset Alzheimer’s disease (EOAD) is rare and understudied. Sporadic early-onset Alzheimer’s disease (EOAD) is rare and understudied. What Question Were You Investigating? What Were Your Findings? Alzheimer’s Dement.

Disease 111
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PET/MRI rules out tau protein in late-life depression

AuntMinnie

A PET/MRI study has provided insights into the neurobiology of late-life depression, with researchers reporting that tau protein – a key protein involved in Alzheimer’s disease – does not appear to be involved in the condition. All patients were of similar ages and all were white.

MRI 96
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New tau PET tracer shows promise in Alzheimer’s disease patients

AuntMinnie

PET imaging using a newly developed radiotracer has identified different patterns of brain tau pathology over time in early-onset versus late-onset Alzheimer’s disease patients, according to a study published February 1 in the Journal of Nuclear Medicine. in 15 patients with negative amyloid PET scans; 1.18 in

Disease 130
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Researchers warn of side effects of new Alzheimer's disease drugs

AuntMinnie

Read more on AuntMinnie.com Related Reading: CMS to cover Alzheimer's drugs for patients enrolled in registry Will lecanemab approval increase PET scan volumes? FDA approves new drug for Alzheimer's disease FDA doubles MRI scans needed for Aduhelm patients MRI sheds light on effects of aducanumab Alzheimer's drug

Disease 52