AuntMinnie

JANUARY 23, 2025

In a recent PET study with unexpected results, patients infected with herpes had fewer signs of brain deposits associated with Alzheimers disease than uninfected patients, a group in France has reported. The study was published January 18 in Scientific Reports. The median age of the group was 74 years old.

Disease 279

Disease PET Scan Diagnose Imaging 279

AuntMinnie

OCTOBER 27, 2023

Patients with less tau pathology on PET scans may respond better to treatment with the new Alzheimer’s disease drug donanemab, according to an October 25 news report in the journal Practical Neurology. Donanemab is a monoclonal antibody designed to bind to beta-amyloid protein that already has formed into plaque deposits.

Disease 298

Disease PET Scan Clinic Diagnose 298

AuntMinnie

NOVEMBER 25, 2024

F-18 florbetaben PET scans for diagnosing Alzheimer’s disease can be reduced from 20 minutes to five minutes without losing accuracy, according to a recent study. Our findings suggest that shorter scan times are a viable and effective option for brain amyloid PET imaging in clinical settings,” the group wrote.

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PET Scan Nuclear Medicine Disease Diagnose 203

AuntMinnie

FEBRUARY 13, 2024

PET scans have revealed specific brain pathology that may drive sleep disturbances in Alzheimer’s disease patients, according to a study published February 8 in the Journal of the Neurological Sciences. Of these, 119 (43%) had normal cognition, 132 (24%) had mild cognitive impairment, and three (2%) had Alzheimer’s disease.

Disease 277

Disease PET Scan Medical Clinic 277

AuntMinnie

APRIL 8, 2025

Deuterium metabolic imaging (DMI) was highly aligned with F-18 FDG-PET -- a cornerstone of dementia diagnostics -- in patients with Alzheimer's disease in a study published April 8 in Radiology. Given that PET scans are more expensive and expose patients to small amounts of radiation, DMI is being explored as an alternative.

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MRI Disease PET Scan Clinic 215

AuntMinnie

JULY 2, 2024

Food and Drug Administration (FDA) has approved Eli Lilly's drug donanemab (Kisunla) for the treatment of early Alzheimer's disease, including mild cognitive impairment or mild dementia. According to clinical trials, amyloid PET scans showed that donanemab reduced amyloid plaques by up to 84% after 18 months of treatment.

Disease 246

Disease PET Scan MRI Clinic 246

AuntMinnie

FEBRUARY 5, 2024

PET imaging using a newly developed radiotracer has identified different patterns of brain tau pathology over time in early-onset versus late-onset Alzheimer’s disease patients, according to a study published February 1 in the Journal of Nuclear Medicine. in 15 patients with negative amyloid PET scans; 1.18 in

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Disease Nuclear Medicine PET Scan IT 325

AuntMinnie

JUNE 7, 2024

Kuo, who led development of imaging guidelines used to develop Lu-177 PSMA-617 ( Pluvicto , Novartis), noted that the theranostics treatment is approved for use in advanced stages of the disease, but that trials are underway to test it in patients at earlier stages. “We last year for Alzheimer's disease.

Disease 264

Disease Nuclear Medicine PET Scan Imaging 264

Radiology Business

JULY 18, 2023

The agency is looking to lift the longstanding NCD that restricts patients to one amyloid-detecting positron emission tomography exam in their lifetime.

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PET Scan Disease 244

AuntMinnie

JULY 18, 2023

Read more on AuntMinnie.com Related Reading: FDA grants full approval to Alzheimer's disease drug Leqembi CMS rethinks limit on PET scans for Alzheimer’s disease patients FDA doubles MRI scans needed for Aduhelm patients CMS to limit coverage of new drugs for Alzheimer's disease CMS scrubs rule restricting PET tracer coverage

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PET Scan Disease Medicare MRI 130

AuntMinnie

APRIL 29, 2024

PET brain scans show persistent brain inflammation in patients with multiple sclerosis (MS), despite being treated with high-efficacy disease-modifying therapies, according to a recent study by researchers in Boston. The researchers performed F-18 PBR06 PET scans on 22 patients with MS and eight healthy controls.

PET Scan 306

PET Scan Nuclear Medicine Disease Clinic 306

AuntMinnie

MAY 31, 2023

PET scans for the first time show brain activity that could potentially explai.

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PET Scan Disease Imaging 130

AuntMinnie

OCTOBER 13, 2023

Centers for Medicare and Medicaid Services (CMS) announced on October 13 that it has lifted its coverage limit of one beta-amyloid PET scan per lifetime for patients with Alzheimer’s disease. Medicare coverage decisions for amyloid PET scans will now be made by local Medicare Administrative Contractors (MACs).

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Nuclear Medicine PET Scan Medicare Disease 290

AuntMinnie

FEBRUARY 12, 2024

Chinese clinicians have provided evidence in a “real-world study” that shows amyloid PET imaging is effective for diagnosing and managing patients with Alzheimer’s disease, according to a study published February 8 in Alzheimer’s and Dementia. of patients, noted lead author Ke-Liang Chen, MD, a neurologist at Fudan University. “In

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PET Scan Diagnose Disease Radiopharmaceuticals 262

AuntMinnie

MARCH 7, 2025

A PET study has revealed that women over the age of 70 who took menopausal hormone therapy (HT) more than a decade before have faster brain tau accumulation -- a key indicator of Alzheimers disease. The findings may inform [Alzheimers disease] risk discussions relating to womens reproductive health and treatment, the group wrote.

Disease 163

Disease PET Scan Pharmaceutical Education 163

Medical Xpress: Radiology

NOVEMBER 7, 2023

In a small study, researchers at the National Institutes of Health have found that positron emission tomography (PET) scans of the heart may identify people who will go on to develop Parkinson's disease or Lewy body dementia among those at-risk for these diseases.

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PET Scan Disease 113

AuntMinnie

AUGUST 29, 2024

Early brain accumulation of amyloid plaque on PET scans is associated with emerging depressive symptoms in cognitively unimpaired older adults, according to a study published August 29 in JAMA Network Open. Their aim in this study was to determine whether these associations persist or progress over time.

PET Scan 279

PET Scan Disease Hospital Imaging 279

AuntMinnie

OCTOBER 18, 2023

A group in France has offered an explanation for long COVID brain fog, with the concept based on a visual brain pattern they discovered on patient PET scans, according to a study published October 13 in Medical Hypotheses. “We A) PET scan of a healthy subject. (B) B) PET scan of a long COVID patient.

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PET Scan Nuclear Medicine Imaging Hospital 363

ScienceDaily

JUNE 27, 2024

The new radiotracer, called FDT, enables PET scans to be used for the first time to accurately pinpoint when and where the disease is still active in a patient's lungs. Radiotracers are radioactive compounds which give off radiation that can be detected by scanners and turned into a 3D image.

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PET Scan Radiation Disease Imaging 115

AuntMinnie

DECEMBER 12, 2023

A PET radiotracer for diagnosing Alzheimer’s disease may also be used to measure vascular brain changes in patients during PET/MRI scans, according to a study published December 7 in the Journal of Nuclear Medicine.

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MRI Nuclear Medicine PET Scan Disease 325

Imaging Technology

APRIL 24, 2024

Microglia are immune cells in the brain that are thought to have a role in MS disease progression but cannot be seen by a routine MRI. The team developed a technique called F18 PBR 06 PET imaging. The newly published study involved performing PET scans on 22 people with MS and eight healthy controls.

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PET Scan Disease Nuclear Medicine Clinic 102

AuntMinnie

NOVEMBER 20, 2023

People with higher amounts of visceral abdominal fat in midlife may be at increased risk of Alzheimer's disease, according to research to be presented at the upcoming RSNA meeting. A subset of 32 patients underwent PET imaging to identify any amyloid plaque and tau tangles that would indicate the development of Alzheimer's disease.

Disease 323

Disease PET Scan MRI Imaging 323

AuntMinnie

JULY 18, 2023

Experts have drafted new diagnostic criteria for Alzheimer's disease to reflec.

Disease 130

Disease Diagnose PET Scan Diagnostic 130

AuntMinnie

JULY 25, 2024

A PET/MRI study has provided insights into the neurobiology of late-life depression, with researchers reporting that tau protein – a key protein involved in Alzheimer’s disease – does not appear to be involved in the condition. Image and caption courtesy of the American Journal of Geriatric Psychiatry.

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MRI PET Scan Disease Diagnose 240

AuntMinnie

JANUARY 30, 2024

MRI is the imaging gold standard for diagnosis, yet identifying the disease using this method remains challenging, the researchers wrote. In all three cases, gadolinium-enhanced MRI scans did not show abnormalities. F-18 FDG-PET and MRI scans of three patients. In our outpatient clinic follow-up (2 to 2.5

Diagnose 270

Diagnose PET Scan MRI Disease 270

AuntMinnie

NOVEMBER 6, 2023

PET imaging has revealed brain pathology linked to faster clinical progression of Alzheimer’s disease in patients with ApoE4 gene variants, according to a study published November 6 in JAMA Neurology.

PET Scan 264

PET Scan Disease Clinic Imaging 264

AuntMinnie

FEBRUARY 9, 2024

In a proof-of-concept study, the researchers used F-18 FDG-PET scans in healthy participants within minutes after they performed standing and walking tasks and identified specific changes in brain glucose metabolism. F-18 FDG-PET scans allow clinicians to measure the brain's energy demands based on glucose metabolism.

PET Scan 278

PET Scan Imaging Disease MRI 278

AuntMinnie

DECEMBER 18, 2023

PET scans typically used for diagnosing prostate cancer may have value in detecting inflammatory bowel disease (IBD), according to a case series published December 8 in Clinical and Experimental Gastroenterology.

Disease 321

Disease PET Scan Diagnose Clinic 321

AuntMinnie

JULY 7, 2023

Read more on AuntMinnie.com Related Reading: CMS to cover Alzheimer's drugs for patients enrolled in registry Will lecanemab approval increase PET scan volumes? FDA approves new drug for Alzheimer's disease CMS delays decision on amyloid PET coverage MRI sheds light on effects of aducanumab Alzheimer's drug

Disease 130

Disease PET Scan MRI 130

AuntMinnie

JULY 1, 2024

Participants underwent both F-18 PSMA-1007 PET/CT and multiparametric MRI within 14 days of one another and at least five days before surgery at two hospitals in Alberta, Canada. Out of 150 men who participated, 134 ultimately underwent radical prostatectomies (the mean age was 62 years old).

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MRI PET Scan Nuclear Medicine Bone Scan 264

AuntMinnie

SEPTEMBER 1, 2023

Read more on AuntMinnie.com Related Reading: CMS to cover Alzheimer's drugs for patients enrolled in registry Will lecanemab approval increase PET scan volumes? FDA approves new drug for Alzheimer's disease FDA doubles MRI scans needed for Aduhelm patients MRI sheds light on effects of aducanumab Alzheimer's drug

Disease 130

Disease PET Scan MRI 130

AuntMinnie

JULY 11, 2023

Read more on AuntMinnie.com Related Reading: FDA grants full approval to Alzheimer's disease drug Leqembi MITA chides CMS on beta-amyloid PET decision CMS to cover Alzheimer's drugs for patients enrolled in registry FDA approves new drug for Alzheimer's disease CMS delays decision on amyloid PET coverage

PET Scan 130

PET Scan Nuclear Medicine Disease 130

AuntMinnie

FEBRUARY 19, 2024

In this case, a 43-year-old man underwent an MRI scan that showed no contrast enhancement, yet hyperintensities were apparent in the patient’s left thalamus and frontoparietal region. Thus, the clinicians performed an additional PET scan with an amino acid radiotracer (F-18 FET) for further diagnosis of a suspected glioma.

Nuclear Medicine 276

Nuclear Medicine PET Scan Imaging MRI 276

AuntMinnie

MARCH 25, 2025

Researchers in Germany have proposed a new approach derived from brain PET imaging for diagnosing and staging Alzheimers disease, according to a study published March 25 in Radiology. They computed fill states for amyloid, tau, and neurodegeneration using percentages of significantly abnormal voxels, the smallest unit in a PET image.

Diagnose 237

Diagnose Disease PET Scan Clinic 237

AuntMinnie

JANUARY 22, 2024

The technology could allow clinicians to detect multiple biomarkers at once and improve the spatial resolution of brain imaging for applications in cancer as well as neurodegenerative disease, according to principal investigator Lars Furenlid, PhD, a professor of medical imaging at the University of Arizona.

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Imaging PET Scan Disease Medical Imaging 241

AuntMinnie

JULY 10, 2024

Centers for Medicare and Medicaid Services (CMS) proposed a new reimbursement plan July 10 for diagnostic PET scans that would provide separate payments for radiopharmaceuticals, as well as an extra payment for hospitals when they use domestically produced technetium-99m (Tc-99m).

Nuclear Medicine 305

Nuclear Medicine Radiopharmaceuticals Imaging Medicare 305

AuntMinnie

APRIL 10, 2023

Read more on AuntMinnie.com Related Reading: NaF-PET shows bone formation in psoriatic arthritis patients PET/MRI provides new insights into knee osteoarthritis NaF-PET reveals aortic wall injuries NaF-PET scans reveal plaque -- and possible risk of stroke Can deep learning monitor lesions on F-18 NaF PET/CT?

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PET Scan Disease Imaging MRI 130