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NIH highlights PET study in Parkinson’s disease

AuntMinnie

National Institutes of Health (NIH) has highlighted a study that shows cardiac PET scans can help identify people at risk for Parkinson’s disease and Lewy body dementia. Significantly, the research supports a “body first” progression model for the diseases, the researchers suggested. “We

Disease 114
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PET links impaired sleep in Alzheimer’s disease patients to tau protein

AuntMinnie

PET scans have revealed specific brain pathology that may drive sleep disturbances in Alzheimer’s disease patients, according to a study published February 8 in the Journal of the Neurological Sciences. Of these, 119 (43%) had normal cognition, 132 (24%) had mild cognitive impairment, and three (2%) had Alzheimer’s disease.

Disease 110
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PET reveals patient responses to new Alzheimer’s disease drug

AuntMinnie

Patients with less tau pathology on PET scans may respond better to treatment with the new Alzheimer’s disease drug donanemab, according to an October 25 news report in the journal Practical Neurology. Donanemab is a monoclonal antibody designed to bind to beta-amyloid protein that already has formed into plaque deposits.

Disease 119
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FDA approves donanemab for Alzheimer's disease

AuntMinnie

Food and Drug Administration (FDA) has approved Eli Lilly's drug donanemab (Kisunla) for the treatment of early Alzheimer's disease, including mild cognitive impairment or mild dementia. According to clinical trials, amyloid PET scans showed that donanemab reduced amyloid plaques by up to 84% after 18 months of treatment.

Disease 98
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Characterizing body fat with MRI helps predict Alzheimer's risk

AuntMinnie

CHICAGO -- Characterizing an individual's type of body fat using body MRI can help predict Alzheimer's disease risk up to 20 years before symptoms manifest, according to research results presented December 2 at the RSNA meeting.

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PET reveals ‘smoldering’ brain inflammation in patients treated for MS

AuntMinnie

PET brain scans show persistent brain inflammation in patients with multiple sclerosis (MS), despite being treated with high-efficacy disease-modifying therapies, according to a recent study by researchers in Boston. The researchers performed F-18 PBR06 PET scans on 22 patients with MS and eight healthy controls.

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New PET Tracer Detects Inflammatory Arthritis Before Symptoms Appear

Imaging Technology

milla1cf Fri, 02/09/2024 - 09:17 February 9, 2024 — A novel PET imaging technique can noninvasively detect active inflammation in the body before clinical symptoms arise, according to research published in the February issue of The Journal of Nuclear Medicine. It is a complex autoimmune disease characterized by chronic inflammation.

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