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Blue Earth Therapeutics Announces Promising Results from Preclinical Evaluation of Synergistic Drug Combinations with Radiopharmaceutical 177Lu-rhPSMA-10.1 for Treatment of Prostate Cancer

Imaging Technology

This may be due to inhibition of the MEK-MAPK pathway during DNA damage response, resulting in radiosensitization of cancer cells to 177Lu-rhPSMA-10.1. Results from this preclinical study presented at AACR demonstrated a synergistic therapeutic effect between 177Lu-rhPSMA-10.1 and an MEK inhibitor.

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Abstract No. 360 Safety of Transarterial Radioembolization Plus Adjuvant Systemic Capecitabine for Treatment of Unresectable Biliary Tract Cancer

JVIR

It also acts as a radiosensitizer that can be combined with transarterial radioembolization (TARE) to treat primary and secondary liver tumors. Capecitabine has been proven effective as adjuvant chemotherapy for resectable biliary tract cancer (BTC).

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TeleDaaS Launches as Premier Provider of Dosimetry as a Service for Clinical Research Organizations

Imaging Technology

I anticipate that the benefit of radiopharmaceuticals will be maximized by combining radiopharmaceutical therapies with a vast array of other agents including immunotherapies, chemotherapeutics, radiosensitizers and radioprotectors. This is already showing promise with several ongoing trials of approved and developmental radiopharmaceuticals.

Clinic 78
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5 Recommendations to Achieve Excellence in Pediatric Medical Imaging

Everything Rad

Not only are children more radiosensitive than adults (the cancer risk per unit dose of ionizing radiation is higher), but children also have a longer expected lifetime, which puts them at greater risk of cancer following radiation exposure.(1) The balance of dose and image quality is even more important in pediatric medical imaging.

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Pediatric Radiology: What To Expect

The Radiology Clinic

Since children are more radiosensitive and prone to the negative repercussions of radiation than adults, technical factors should be modified to limit radiation to ONLY what’s necessary for diagnosis. These “pieces” are the two epiphyseal plates of the femur. These will fuse later in life and appear more like the adult femur image.

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CEUS adds to locoregional therapy for liver disease

AuntMinnie

This puts shear stress on the tumor endothelium and activates the production of ceramide, a radiosensitizer. Corinne Wessner from Thomas Jefferson University discusses early study results at UltraCon showing the potential of ultrasound-triggered microbubble destruction in treating liver disease. The average tumor diameter recorded was 4.2

Disease 279