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PETscans performed at one or three months after patients with large B-cell lymphoma begin chimeric antigen receptor T-cell (CAR T-cell) therapy can indicate whether they are responding to the treatment, according to a study published April 17 in the Journal of Nuclear Medicine. A visual abstract of the study.
In 2023 compared with 2022, the total volume of positron emission tomography (PET) scans increased 10.2% year over year, according to the newly published IMV 2024 PET Market Summary Report. In 2023, the average number of PETscans per fixed PET site (versus mobile PET) increased 6.7%
Alzheimer’s disease patients with cognitive impairment or dementia who were referred for amyloid PETscans had fewer hospitalizations compared with a matched control group, according to a study published October 9 in JAMA Neurology. Each participant was matched to a control Medicare beneficiary who had not undergone amyloid PET.
Men should have prostate-specific membrane antigen (PSMA) PETscans about eight months after undergoing external beam radiotherapy for prostate cancer, a group at the University of California, Los Angeles has reported. The median duration between the first PETscan and the end-date of radiotherapy was 2.3
F-18 fluoroestradiol (FES)-PETscans can predict whether or not endocrine therapy may be effective in women with estrogen receptor (ER)-positive breast cancer, according to a study published March 13 in the Journal of Nuclear Medicine. A visual abstract of the analysis. A visual abstract of the analysis.
Thus, the researchers aimed to determine prospectively whether 18F-FES PET improves staging for patients with clinical stage II/III or local-regional recurrent, grade 1 or 2, ER-positive breast cancer compared with standard F-18 FDG-PET. The tumor in the right breast (T4N0M0, grade 3 ductal carcinoma) is visible on both PETscans.
That’s according to new PET imaging that shows the presence of activated T cells in the brain, spinal cord, gut and lung tissues of individuals who have recovered from COVID.
F-18 florbetaben PETscans for diagnosing Alzheimer’s disease can be reduced from 20 minutes to five minutes without losing accuracy, according to a recent study. Our findings suggest that shorter scan times are a viable and effective option for brain amyloid PET imaging in clinical settings,” the group wrote.
The finding is from an analysis of 300 participants who underwent multiple F-18 flortaucipir tau PETscans between 2015 and 2022 and suggests depression could be a modifiable risk factor for the disease, noted lead author Daniel Talmasov, MD, and colleagues.
The research included 62 cognitively healthy individuals (average age, 50) who underwent a brain PETscan, body MRI, and metabolic assessment. They conducted a study that investigated any links between "modifiable lifestyle-related factors" such as obesity, body fat distribution and metabolic aspects, and Alzheimer's disease.
Over the same period between the two years, the average number of PETscans performed per installed fixed PET/CT systems increased by 8.2% -- a finding that indicates that much of the increased procedure volumes have been absorbed by existing PET system capacity. Davin Korstjens of IMV Medical Information Division.
“With further tuning and validation, this pipeline may potentially add value in cancer screening, staging, diagnosis and prognosis," experts wrote in Cell Reports Medicine.
The OIG also reported the following: Community care staff did not make "timely, sufficient efforts to retrieve the patient's PETscan results." Furthermore, although the healthcare system conducted an "institutional disclosure" to the patient, this documentation didn't include key details.
A PET study by researchers at the National Institutes of Health (NIH) has called into question the theory that ultraprocessed foods elicit brain responses akin to addictive drugs. Participants fasted for 12 hours before the first scan. Participants completed a five-day inpatient stay during which their diets were stabilized.
The agency is looking to lift the longstanding NCD that restricts patients to one amyloid-detecting positron emission tomography exam in their lifetime.
PETScanning, like all other modalities of imaging equipment, has made strides in improving diagnostic accuracy. The biggest step in that direction for PET has been the development and proliferation of Time-of-Flight technology.
The algorithm allows for faster PETscanning, up to 75% faster without compromising image quality, according to the company. Telix’s leading PSMA-PET imaging kit, Illucix, is used to perform gallium-68 PSMA-11 imaging exams in men with prostate cancer.
Read more on AuntMinnie.com Related Reading: FDA grants full approval to Alzheimer's disease drug Leqembi CMS rethinks limit on PETscans for Alzheimer’s disease patients FDA doubles MRI scans needed for Aduhelm patients CMS to limit coverage of new drugs for Alzheimer's disease CMS scrubs rule restricting PET tracer coverage
Providers have reported issues with one Medicare Administrative Contractor covering PETscans, for example, with reimbursement falling significantly below the expense.
A group in France has offered an explanation for long COVID brain fog, with the concept based on a visual brain pattern they discovered on patient PETscans, according to a study published October 13 in Medical Hypotheses. “We A) PETscan of a healthy subject. (B) B) PETscan of a long COVID patient.
The new radiotracer, called FDT, enables PETscans to be used for the first time to accurately pinpoint when and where the disease is still active in a patient's lungs. The team has developed a new radiotracer, which is taken up by live TB bacteria in the body.
Chinese clinicians have provided evidence in a “real-world study” that shows amyloid PET imaging is effective for diagnosing and managing patients with Alzheimer’s disease, according to a study published February 8 in Alzheimer’s and Dementia. The clinical utility of amyloid PETscans has been systematically studied in many other countries.
Centers for Medicare and Medicaid Services (CMS) announced on October 13 that it has lifted its coverage limit of one beta-amyloid PETscan per lifetime for patients with Alzheimer’s disease. Medicare coverage decisions for amyloid PETscans will now be made by local Medicare Administrative Contractors (MACs).
The researchers performed F-18 PBR06 PETscans on 22 patients with MS and eight healthy controls. According to the analysis, glial activity on F-18 PBR06 PETscans was higher in patients with MS than healthy controls in cortical gray matter (+33%) and white matter (+48%). Image courtesy of Clinical Nuclear Medicine.
All subjects underwent 90 minute dynamic whole-body PETscans using a dedicated research scanner called PennPET Explorer. Prior to PETscanning, subjects also underwent T1-weighted MRI brain imaging to create templates to segment the PET brain data into 10 regions of interest.
CT Scans: Provides cross-sectional images of the body for a more detailed view. PETScans : Help detect diseases at a cellular level, often used for cancer detection and brain disorders. Ultrasound : Uses sound waves to create images, often used during pregnancy or to check organs. How Does Early Detection Help?
Florida resident Rick Nassenstein allegedly “played a central role” in a scheme that involved paying physicians “exorbitant” fees to refer patients for PETscans.
Two experts review SNMMI (Society of Nuclear Medicine and Molecular Imaging) guidelines for use of PSMA PETscans in prostate cancer detection, as well as awareness about this new modality within the patient community.
The newly published study involved performing PETscans on 22 people with MS and eight healthy controls. Researchers measured the glial activity load on the PETscans, a new measure developed in Singhal’s lab where lab members looked at the level of smoldering inflammation from microglia in MS patients.
PETscans have revealed specific brain pathology that may drive sleep disturbances in Alzheimer’s disease patients, according to a study published February 8 in the Journal of the Neurological Sciences. Nonetheless, the results have several implications for clinical practice, they wrote.
The accumulation of brain amyloid deposits is a mechanism underlying Alzheimers disease, with amyloid PETscans used to diagnose the disease. To address the knowledge gap, the group identified 182 out of 1,680 participants in an Alzheimers disease study in France and Monaco who had both PETscans and HSV-1 blood tests available.
Early brain accumulation of amyloid plaque on PETscans is associated with emerging depressive symptoms in cognitively unimpaired older adults, according to a study published August 29 in JAMA Network Open. The mean follow-up period was 8.6
In a small study, researchers at the National Institutes of Health have found that positron emission tomography (PET) scans of the heart may identify people who will go on to develop Parkinson's disease or Lewy body dementia among those at-risk for these diseases.
Similar to F-18 FDG-PET, the technique targets glucose metabolism specifically its downstream metabolites, lactate (Lac), glutamate and glutamine (Glx), which function abnormally in Alzheimers disease. Given that PETscans are more expensive and expose patients to small amounts of radiation, DMI is being explored as an alternative.
A group in England has established PET imaging as a new approach for studying gait – an excellent indicator of physical, emotional, and mental health, according to a study published February 6 in NeuroImage. F-18 FDG-PETscans allow clinicians to measure the brain's energy demands based on glucose metabolism.
Patients with less tau pathology on PETscans may respond better to treatment with the new Alzheimer’s disease drug donanemab, according to an October 25 news report in the journal Practical Neurology. Research suggests that the accumulation of these proteins is a continuous process that starts decades before the onset of symptoms.
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